1ndn

<StructureSection load='1ndn' size='340' side='right' caption='[[1ndn]], [[Resolution|resolution]] 3.00&Aring;' scene=''>

<table><tr><td colspan='2'>[[1ndn]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NDN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NDN FirstGlance]. <br>

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ndn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ndn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ndn RCSB], [http://www.ebi.ac.uk/pdbsum/1ndn PDBsum]</span></td></tr>

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== Publication Abstract from PubMed ==

The molecular structure of a nicked dodecamer DNA double helix, made of a ternary system containing d(CGCGAAAACGCG) + d(CGCGTT) + d(TTCGCG) oligonucleotides, has been determined by x-ray diffraction analysis at 3 A resolution. The molecule adopts a B-DNA conformation, not unlike those found in intact dodecamer DNA molecules crystallized in a somewhat different crystal lattice, despite a gap due to the absence of a phosphate group in the molecule. The helix has a distinct narrow minor groove near the center of the molecule at the AAAA region. This suggests that the internal stabilizing forces due to base stacking and hydrogen-bonding interactions are sufficient to overcome the loss of connectivity associated with the disruption of the covalent backbone of DNA.

Molecular structure of nicked DNA: a substrate for DNA repair enzymes.,Aymami J, Coll M, van der Marel GA, van Boom JH, Wang AH, Rich A Proc Natl Acad Sci U S A. 1990 Apr;87(7):2526-30. PMID:2320572<ref>PMID:2320572</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>

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== References ==

<references/>

[[Category: Aymani, J]]

[[Category: Boom, J H.Van]]

[[Category: Coll, M]]

[[Category: Marel, G A.Van Der]]

[[Category: Rich, A]]

[[Category: Wang, A H.J]]

[[Category: B-dna]]

[[Category: Nicked]]