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1ne8

From Proteopedia

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[[Image:1ne8.png|left|200px]]
 
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{{STRUCTURE_1ne8| PDB=1ne8 | SCENE= }}
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==YDCE protein from Bacillus subtilis==
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<StructureSection load='1ne8' size='340' side='right'caption='[[1ne8]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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===YDCE protein from Bacillus subtilis===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1ne8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NE8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NE8 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PG:2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL'>1PG</scene>, <scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene></td></tr>
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[[1ne8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NE8 OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ne8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ne8 OCA], [https://pdbe.org/1ne8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ne8 RCSB], [https://www.ebi.ac.uk/pdbsum/1ne8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ne8 ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1ne8 TOPSAN]</span></td></tr>
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</table>
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==Reference==
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== Function ==
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<ref group="xtra">PMID:014517982</ref><references group="xtra"/>
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[https://www.uniprot.org/uniprot/ENDOA_BACSU ENDOA_BACSU] Toxic component of a toxin-antitoxin (TA) module. Has specificity for UACAU sequences, claving after the first U and yielding cleavage products with 3' phosphate and 5' hydroxyl groups. Overexpression is toxic for cell growth, probably by inhibiting protein synthesis through the cleavage of single-stranded RNA. The toxicity is reversed by the antitoxin EndoAI. Toxin activity cannot be inhibited by MazE from E.coli.<ref>PMID:15882409</ref> <ref>PMID:21763692</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ne/1ne8_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ne8 ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Bahna, F.]]
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[[Category: Large Structures]]
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[[Category: Burley, S K.]]
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[[Category: Bahna F]]
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[[Category: Gogos, A.]]
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[[Category: Burley SK]]
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[[Category: Gomez, C A.]]
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[[Category: Gogos A]]
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[[Category: Mu, H.]]
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[[Category: Gomez CA]]
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[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics.]]
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[[Category: Mu H]]
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[[Category: Shapiro, L.]]
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[[Category: Shapiro L]]
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[[Category: Conserved hypothetical protein ydce]]
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[[Category: New york sgx research center for structural genomic]]
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[[Category: Nysgxrc]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Structural genomic]]
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[[Category: Unknown function]]
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Current revision

YDCE protein from Bacillus subtilis

PDB ID 1ne8

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OCA

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