1nkd

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{{Seed}}
 
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[[Image:1nkd.png|left|200px]]
 
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==ATOMIC RESOLUTION (1.07 ANGSTROMS) STRUCTURE OF THE ROP MUTANT <2AA>==
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The line below this paragraph, containing "STRUCTURE_1nkd", creates the "Structure Box" on the page.
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<StructureSection load='1nkd' size='340' side='right'caption='[[1nkd]], [[Resolution|resolution]] 1.09&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1nkd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NKD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NKD FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.09&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nkd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nkd OCA], [https://pdbe.org/1nkd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nkd RCSB], [https://www.ebi.ac.uk/pdbsum/1nkd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nkd ProSAT]</span></td></tr>
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{{STRUCTURE_1nkd| PDB=1nkd | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ROP_ECOLX ROP_ECOLX] Regulates plasmid DNA replication by modulating the initiation of transcription of the primer RNA precursor. Processing of the precursor of the primer, RNAII, is inhibited by hydrogen bonding of RNAII to its complementary sequence in RNAI. ROP increases the affinity of RNAI for RNAII and thus decreases the rate of replication initiation events.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nk/1nkd_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nkd ConSurf].
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<div style="clear:both"></div>
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===ATOMIC RESOLUTION (1.07 ANGSTROMS) STRUCTURE OF THE ROP MUTANT <2AA>===
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==See Also==
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*[[Rop protein|Rop protein]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_10089502}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 10089502 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10089502}}
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==About this Structure==
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1NKD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NKD OCA].
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==Reference==
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Structural parameters for proteins derived from the atomic resolution (1.09 A) structure of a designed variant of the ColE1 ROP protein., Vlassi M, Dauter Z, Wilson KS, Kokkinidis M, Acta Crystallogr D Biol Crystallogr. 1998 Nov 1;54(Pt 6 Pt 2):1245-60. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10089502 10089502]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Kokkinidis, M.]]
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[[Category: Kokkinidis M]]
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[[Category: Vlassi, M.]]
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[[Category: Vlassi M]]
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[[Category: 4-alpha-helix bundle]]
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[[Category: Atomic resolution structure]]
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[[Category: Transcription regulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 15 15:12:55 2008''
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Current revision

ATOMIC RESOLUTION (1.07 ANGSTROMS) STRUCTURE OF THE ROP MUTANT <2AA>

PDB ID 1nkd

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