1odd

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(New page: 200px<br /><applet load="1odd" size="450" color="white" frame="true" align="right" spinBox="true" caption="1odd, resolution 2.2&Aring;" /> '''OMPR C-TERMINAL DOMAI...)
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[[Image:1odd.jpg|left|200px]]<br /><applet load="1odd" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1odd, resolution 2.2&Aring;" />
 
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'''OMPR C-TERMINAL DOMAIN (OMPR-C) FROM ESCHERICHIA COLI'''<br />
 
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==Overview==
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==OMPR C-TERMINAL DOMAIN (OMPR-C) FROM ESCHERICHIA COLI==
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The C-terminal DNA-binding domain of OmpR, a positive regulator involved, in osmoregulation expression of the ompF and ompC genes in Escherichia, coli, has a helix-turn-helix variant motif. The 'turn' region, consisting, of 11 residues, forms an RNA polymerase contact site.
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<StructureSection load='1odd' size='340' side='right'caption='[[1odd]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[1odd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ODD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ODD FirstGlance]. <br>
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1ODD is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1ODD OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1odd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1odd OCA], [https://pdbe.org/1odd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1odd RCSB], [https://www.ebi.ac.uk/pdbsum/1odd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1odd ProSAT]</span></td></tr>
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==Reference==
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</table>
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Escherichia coli positive regulator OmpR has a large loop structure at the putative RNA polymerase interaction site., Kondo H, Nakagawa A, Nishihira J, Nishimura Y, Mizuno T, Tanaka I, Nat Struct Biol. 1997 Jan;4(1):28-31. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8989318 8989318]
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== Function ==
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[[Category: Escherichia coli]]
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[https://www.uniprot.org/uniprot/OMPR_ECOLI OMPR_ECOLI] The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the OmpR protein. As a multimer, it turns on the expression of the ompC gene; as a monomer, it turns on the expression of the ompF gene.
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[[Category: Single protein]]
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== Evolutionary Conservation ==
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[[Category: Kondou, H.]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Nakagawa, A.]]
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Check<jmol>
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[[Category: Tanaka, I.]]
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<jmolCheckbox>
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[[Category: dna binding domain]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/od/1odd_consurf.spt"</scriptWhenChecked>
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[[Category: gene regulatory protein]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: positive response regulator]]
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 22:55:36 2007''
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1odd ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Escherichia coli K-12]]
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[[Category: Large Structures]]
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[[Category: Kondou H]]
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[[Category: Nakagawa A]]
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[[Category: Tanaka I]]

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OMPR C-TERMINAL DOMAIN (OMPR-C) FROM ESCHERICHIA COLI

PDB ID 1odd

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