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1p1y

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[[Image:1p1y.gif|left|200px]]
 
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==Crystal structure of a continuous three-dimensional DNA lattice from d(GGACAGATGGGAG)==
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The line below this paragraph, containing "STRUCTURE_1p1y", creates the "Structure Box" on the page.
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<StructureSection load='1p1y' size='340' side='right'caption='[[1p1y]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1p1y]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P1Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P1Y FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BRU:5-BROMO-2-DEOXYURIDINE-5-MONOPHOSPHATE'>BRU</scene>, <scene name='pdbligand=CBR:5-BROMO-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>CBR</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_1p1y| PDB=1p1y | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p1y OCA], [https://pdbe.org/1p1y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p1y RCSB], [https://www.ebi.ac.uk/pdbsum/1p1y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p1y ProSAT]</span></td></tr>
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</table>
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'''Crystal structure of a continuous three-dimensional DNA lattice from d(GGACAGATGGGAG)'''
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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==Overview==
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[[Category: Birktoft JJ]]
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DNA has proved to be a versatile material for the rational design and assembly of nanometer scale objects. Here we report the crystal structure of a continuous three-dimensional DNA lattice formed by the self-assembly of a DNA 13-mer. The structure consists of stacked layers of parallel helices with adjacent layers linked through parallel-stranded base pairing. The hexagonal lattice geometry contains solvent channels that appear large enough to allow 3'-linked guest molecules into the crystal. We have successfully used these parallel base pairs to design and produce crystals with greatly enlarged solvent channels. This lattice may have applications as a molecular scaffold for structure determination of guest molecules, as a molecular sieve, or in the assembly of molecular electronics. Predictable non-Watson-Crick base pairs, like those described here, may present a new tool in structural DNA nanotechnology.
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[[Category: Nowakowski J]]
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[[Category: Paukstelis PJ]]
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==About this Structure==
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[[Category: Seeman NC]]
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P1Y OCA].
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==Reference==
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Crystal structure of a continuous three-dimensional DNA lattice., Paukstelis PJ, Nowakowski J, Birktoft JJ, Seeman NC, Chem Biol. 2004 Aug;11(8):1119-26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15324813 15324813]
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[[Category: Birktoft, J J.]]
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[[Category: Nowakowski, J.]]
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[[Category: Paukstelis, P J.]]
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[[Category: Seeman, N C.]]
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[[Category: Continuous three-dimensional dna lattice]]
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[[Category: Parallel-stranded base pair]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 04:34:46 2008''
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Current revision

Crystal structure of a continuous three-dimensional DNA lattice from d(GGACAGATGGGAG)

PDB ID 1p1y

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