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1p43

From Proteopedia

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{{Seed}}
 
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[[Image:1p43.png|left|200px]]
 
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==REVERSE PROTONATION IS THE KEY TO GENERAL ACID-BASE CATALYSIS IN ENOLASE==
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The line below this paragraph, containing "STRUCTURE_1p43", creates the "Structure Box" on the page.
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<StructureSection load='1p43' size='340' side='right'caption='[[1p43]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1p43]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P43 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P43 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2PG:2-PHOSPHOGLYCERIC+ACID'>2PG</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_1p43| PDB=1p43 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p43 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p43 OCA], [https://pdbe.org/1p43 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p43 RCSB], [https://www.ebi.ac.uk/pdbsum/1p43 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p43 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ENO1_YEAST ENO1_YEAST]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p4/1p43_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1p43 ConSurf].
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<div style="clear:both"></div>
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===REVERSE PROTONATION IS THE KEY TO GENERAL ACID-BASE CATALYSIS IN ENOLASE===
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==See Also==
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*[[Enolase 3D structures|Enolase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12846578}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 12846578 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12846578}}
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==About this Structure==
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1P43 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P43 OCA].
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==Reference==
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Reverse protonation is the key to general acid-base catalysis in enolase., Sims PA, Larsen TM, Poyner RR, Cleland WW, Reed GH, Biochemistry. 2003 Jul 15;42(27):8298-306. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12846578 12846578]
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[[Category: Phosphopyruvate hydratase]]
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[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Single protein]]
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[[Category: Cleland WW]]
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[[Category: Cleland, W W.]]
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[[Category: Larsen TM]]
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[[Category: Larsen, T M.]]
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[[Category: Poyner RR]]
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[[Category: Poyner, R R.]]
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[[Category: Reed GH]]
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[[Category: Reed, G H.]]
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[[Category: Sims PA]]
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[[Category: Sims, P A.]]
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[[Category: Beta barrel]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 15:25:12 2008''
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Current revision

REVERSE PROTONATION IS THE KEY TO GENERAL ACID-BASE CATALYSIS IN ENOLASE

PDB ID 1p43

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