This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1pe7

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:07, 14 February 2024) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
==Thermolysin with bicyclic inhibitor==
==Thermolysin with bicyclic inhibitor==
-
<StructureSection load='1pe7' size='340' side='right' caption='[[1pe7]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
+
<StructureSection load='1pe7' size='340' side='right'caption='[[1pe7]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1pe7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PE7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PE7 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1pe7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PE7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PE7 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4BR:2-(4-METHYLPHENOXY)ETHYLPHOSPHINATE'>4BR</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=LEN:3-METHYLBUTAN-1-AMINE'>LEN</scene>, <scene name='pdbligand=LEU:LEUCINE'>LEU</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1pe5|1pe5]], [[1pe8|1pe8]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4BR:2-(4-METHYLPHENOXY)ETHYLPHOSPHINATE'>4BR</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=LEN:3-METHYLBUTAN-1-AMINE'>LEN</scene>, <scene name='pdbligand=LEU:LEUCINE'>LEU</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thermolysin Thermolysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.27 3.4.24.27] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pe7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pe7 OCA], [https://pdbe.org/1pe7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pe7 RCSB], [https://www.ebi.ac.uk/pdbsum/1pe7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pe7 ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1pe7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pe7 OCA], [http://pdbe.org/1pe7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1pe7 RCSB], [http://www.ebi.ac.uk/pdbsum/1pe7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1pe7 ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/THER_BACTH THER_BACTH]] Extracellular zinc metalloprotease.
+
[https://www.uniprot.org/uniprot/THER_BACTH THER_BACTH] Extracellular zinc metalloprotease.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 23: Line 22:
==See Also==
==See Also==
-
*[[Thermolysin|Thermolysin]]
+
*[[Thermolysin 3D structures|Thermolysin 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus thermoproteolyticus]]
[[Category: Bacillus thermoproteolyticus]]
-
[[Category: Thermolysin]]
+
[[Category: Large Structures]]
-
[[Category: Bartlett, P A]]
+
[[Category: Bartlett PA]]
-
[[Category: Juers, D]]
+
[[Category: Juers D]]
-
[[Category: Matthews, B W]]
+
[[Category: Matthews BW]]
-
[[Category: Yusuff, N]]
+
[[Category: Yusuff N]]
-
[[Category: Hydrolase]]
+
-
[[Category: Metalloprotease]]
+

Current revision

Thermolysin with bicyclic inhibitor

PDB ID 1pe7

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools