1q1h

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{{Seed}}
 
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[[Image:1q1h.png|left|200px]]
 
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==An extended winged helix domain in general transcription factor E/IIE alpha==
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The line below this paragraph, containing "STRUCTURE_1q1h", creates the "Structure Box" on the page.
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<StructureSection load='1q1h' size='340' side='right'caption='[[1q1h]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1q1h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q1H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Q1H FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1q1h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q1h OCA], [https://pdbe.org/1q1h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1q1h RCSB], [https://www.ebi.ac.uk/pdbsum/1q1h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1q1h ProSAT]</span></td></tr>
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{{STRUCTURE_1q1h| PDB=1q1h | SCENE= }}
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</table>
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== Function ==
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===An extended winged helix domain in general transcription factor E/IIE alpha===
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[https://www.uniprot.org/uniprot/TFE_SACS2 TFE_SACS2] Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.<ref>PMID:11258705</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 13679366 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q1/1q1h_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_13679366}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1q1h ConSurf].
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1Q1H is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q1H OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:13679366</ref><references group="xtra"/>
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__TOC__
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[[Category: Sulfolobus solfataricus]]
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</StructureSection>
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[[Category: Blobel, J.]]
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[[Category: Large Structures]]
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[[Category: Cramer, P.]]
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[[Category: Saccharolobus solfataricus]]
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[[Category: Meinhart, A.]]
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[[Category: Blobel J]]
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[[Category: Preinitiation complex]]
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[[Category: Cramer P]]
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[[Category: Promoter melting]]
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[[Category: Meinhart A]]
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[[Category: Rna polymerase ii]]
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[[Category: Tfe]]
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[[Category: Tfiie]]
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[[Category: Tfiih]]
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[[Category: Transcription bubble]]
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[[Category: Transcription initiation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 05:23:15 2009''
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Current revision

An extended winged helix domain in general transcription factor E/IIE alpha

PDB ID 1q1h

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