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1q52

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{{Seed}}
 
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[[Image:1q52.png|left|200px]]
 
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==Crystal Structure of Mycobacterium tuberculosis MenB, a Key Enzyme in Vitamin K2 Biosynthesis==
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The line below this paragraph, containing "STRUCTURE_1q52", creates the "Structure Box" on the page.
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<StructureSection load='1q52' size='340' side='right'caption='[[1q52]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1q52]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q52 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Q52 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1q52 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q52 OCA], [https://pdbe.org/1q52 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1q52 RCSB], [https://www.ebi.ac.uk/pdbsum/1q52 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1q52 ProSAT]</span></td></tr>
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{{STRUCTURE_1q52| PDB=1q52 | SCENE= }}
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</table>
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== Function ==
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===Crystal Structure of Mycobacterium tuberculosis MenB, a Key Enzyme in Vitamin K2 Biosynthesis===
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[https://www.uniprot.org/uniprot/MENB_MYCTU MENB_MYCTU] Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).<ref>PMID:12909628</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_12909628}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 12909628 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q5/1q52_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_12909628}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1q52 ConSurf].
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1Q52 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q52 OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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Crystal structure of Mycobacterium tuberculosis MenB, a key enzyme in vitamin K2 biosynthesis., Truglio JJ, Theis K, Feng Y, Gajda R, Machutta C, Tonge PJ, Kisker C, J Biol Chem. 2003 Oct 24;278(43):42352-60. Epub 2003 Aug 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12909628 12909628]
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__TOC__
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[[Category: Mycobacterium tuberculosis h37rv]]
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</StructureSection>
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[[Category: Naphthoate synthase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Feng, Y.]]
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[[Category: Feng Y]]
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[[Category: Gajda, R.]]
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[[Category: Gajda R]]
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[[Category: Kisker, C.]]
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[[Category: Kisker C]]
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[[Category: Machutta, C.]]
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[[Category: Machutta C]]
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[[Category: TBSGC, TB Structural Genomics Consortium.]]
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[[Category: Theis K]]
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[[Category: Theis, K.]]
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[[Category: Tonge PJ]]
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[[Category: Tonge, P J.]]
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[[Category: Truglio JJ]]
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[[Category: Truglio, J J.]]
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[[Category: Lyase]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Structural genomic]]
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[[Category: Tb structural genomics consortium]]
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[[Category: Tbsgc]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 16:06:46 2008''
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Current revision

Crystal Structure of Mycobacterium tuberculosis MenB, a Key Enzyme in Vitamin K2 Biosynthesis

PDB ID 1q52

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