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1qd5

From Proteopedia

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[[Image:1qd5.png|left|200px]]
 
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{{STRUCTURE_1qd5| PDB=1qd5 | SCENE= }}
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==OUTER MEMBRANE PHOSPHOLIPASE A FROM ESCHERICHIA COLI==
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<StructureSection load='1qd5' size='340' side='right'caption='[[1qd5]], [[Resolution|resolution]] 2.17&Aring;' scene=''>
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===OUTER MEMBRANE PHOSPHOLIPASE A FROM ESCHERICHIA COLI===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1qd5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QD5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QD5 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_10537112}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.17&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qd5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qd5 OCA], [https://pdbe.org/1qd5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qd5 RCSB], [https://www.ebi.ac.uk/pdbsum/1qd5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qd5 ProSAT]</span></td></tr>
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[[1qd5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QD5 OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/PA1_ECOLI PA1_ECOLI] Has broad substrate specificity including hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Strong expression leads to outer membrane breakdown and cell death; is dormant in normal growing cells. Required for efficient secretion of bacteriocins.
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<ref group="xtra">PMID:010537112</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qd/1qd5_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qd5 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Blaauw, M.]]
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[[Category: Large Structures]]
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[[Category: Dekker, N.]]
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[[Category: Blaauw M]]
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[[Category: Dijkstra, B W.]]
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[[Category: Dekker N]]
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[[Category: Egmond, M R.]]
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[[Category: Dijkstra BW]]
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[[Category: Kalk, K H.]]
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[[Category: Egmond MR]]
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[[Category: Snijder, H J.]]
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[[Category: Kalk KH]]
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[[Category: Ubarretxena-Belandia, I.]]
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[[Category: Snijder HJ]]
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[[Category: Verheij, H M.]]
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[[Category: Ubarretxena-Belandia I]]
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[[Category: Anti-parallel beta barrel]]
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[[Category: Verheij HM]]
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[[Category: Membrane phospholipase]]
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[[Category: Membrane protein]]
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Current revision

OUTER MEMBRANE PHOSPHOLIPASE A FROM ESCHERICHIA COLI

PDB ID 1qd5

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