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1qe3

From Proteopedia

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{{Seed}}
 
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[[Image:1qe3.png|left|200px]]
 
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<!--
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==PNB ESTERASE==
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The line below this paragraph, containing "STRUCTURE_1qe3", creates the "Structure Box" on the page.
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<StructureSection load='1qe3' size='340' side='right'caption='[[1qe3]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1qe3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QE3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QE3 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_1qe3| PDB=1qe3 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qe3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qe3 OCA], [https://pdbe.org/1qe3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qe3 RCSB], [https://www.ebi.ac.uk/pdbsum/1qe3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qe3 ProSAT]</span></td></tr>
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</table>
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===PNB ESTERASE===
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== Function ==
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[https://www.uniprot.org/uniprot/PNBA_BACSU PNBA_BACSU] Catalyzes hydrolysis of several beta-lactam antibiotic PNB esters to the corresponding free acid and PNB alcohol.
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== Evolutionary Conservation ==
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<!--
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_10535917}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 10535917 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qe/1qe3_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_10535917}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1QE3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QE3 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qe3 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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A structural view of evolutionary divergence., Spiller B, Gershenson A, Arnold FH, Stevens RC, Proc Natl Acad Sci U S A. 1999 Oct 26;96(22):12305-10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10535917 10535917]
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</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Arnold, F.]]
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[[Category: Arnold F]]
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[[Category: Gershenson, A.]]
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[[Category: Gershenson A]]
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[[Category: Spiller, B.]]
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[[Category: Spiller B]]
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[[Category: Stevens, R.]]
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[[Category: Stevens R]]
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[[Category: Alpha-beta hydrolase directed evolution]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 16:14:14 2008''
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Current revision

PNB ESTERASE

PDB ID 1qe3

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