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1qrv

From Proteopedia

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{{Seed}}
 
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[[Image:1qrv.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF THE COMPLEX OF HMG-D AND DNA==
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The line below this paragraph, containing "STRUCTURE_1qrv", creates the "Structure Box" on the page.
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<StructureSection load='1qrv' size='340' side='right'caption='[[1qrv]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1qrv]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QRV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QRV FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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{{STRUCTURE_1qrv| PDB=1qrv | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qrv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qrv OCA], [https://pdbe.org/1qrv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qrv RCSB], [https://www.ebi.ac.uk/pdbsum/1qrv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qrv ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HMGD_DROME HMGD_DROME] Binds preferentially single-stranded DNA and unwinds double stranded DNA. Prefers sites containing the sequence 5'-ttg-3'. Facilitates DNA bending. Associated with early embryonic chromatin in the absence of histone H1.<ref>PMID:1373803</ref> <ref>PMID:8168480</ref> <ref>PMID:7720717</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qr/1qrv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qrv ConSurf].
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<div style="clear:both"></div>
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===CRYSTAL STRUCTURE OF THE COMPLEX OF HMG-D AND DNA===
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==See Also==
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*[[High mobility group protein|High mobility group protein]]
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_10581235}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 10581235 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_10581235}}
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==About this Structure==
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1QRV is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QRV OCA].
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==Reference==
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The structure of a chromosomal high mobility group protein-DNA complex reveals sequence-neutral mechanisms important for non-sequence-specific DNA recognition., Murphy FV 4th, Sweet RM, Churchill ME, EMBO J. 1999 Dec 1;18(23):6610-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10581235 10581235]
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[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Churchill, M E.A.]]
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[[Category: Churchill MEA]]
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[[Category: IV, F V.Murphy.]]
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[[Category: Murphy IV FV]]
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[[Category: Sweet, R M.]]
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[[Category: Sweet RM]]
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[[Category: Hmg domain]]
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[[Category: Non-sequence specific chromosomal protein hmg-d]]
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[[Category: Protein-dna complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 12:43:09 2008''
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Current revision

CRYSTAL STRUCTURE OF THE COMPLEX OF HMG-D AND DNA

PDB ID 1qrv

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