1qsp

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[[Image:1qsp.png|left|200px]]
 
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{{STRUCTURE_1qsp| PDB=1qsp | SCENE= }}
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==CRYSTAL STRUCTURE OF THE YEAST PHOSPHORELAY PROTEIN YPD1==
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<StructureSection load='1qsp' size='340' side='right'caption='[[1qsp]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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===CRYSTAL STRUCTURE OF THE YEAST PHOSPHORELAY PROTEIN YPD1===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1qsp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QSP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QSP FirstGlance]. <br>
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{{ABSTRACT_PUBMED_10512701}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qsp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qsp OCA], [https://pdbe.org/1qsp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qsp RCSB], [https://www.ebi.ac.uk/pdbsum/1qsp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qsp ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1qsp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QSP OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/YPD1_YEAST YPD1_YEAST] Phosphorelay intermediate protein that is part of the branched SLN1-YPD1-SKN7/SSK1 two-component regulatory system, which controls activity of the HOG1 pathway and gene expression in response to changes in the osmolarity of the extracellular environment. Catalyzes the phosphoryl group transfer from the membrane-bound osmosensing histidine kinase SLN1 to two distinct response regulator proteins, SSK1 in the cytoplasm, and transcription factor SKN7 in the nucleus.<ref>PMID:11073911</ref> <ref>PMID:9843501</ref>
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==Reference==
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== Evolutionary Conservation ==
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<ref group="xtra">PMID:010512701</ref><references group="xtra"/>
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qs/1qsp_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qsp ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: West, A H.]]
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[[Category: West AH]]
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[[Category: Xu, Q.]]
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[[Category: Xu Q]]
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[[Category: Four-helix bundle]]
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[[Category: Signaling protein]]
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[[Category: Two- component signal transduction]]
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CRYSTAL STRUCTURE OF THE YEAST PHOSPHORELAY PROTEIN YPD1

PDB ID 1qsp

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