This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1r6b

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:20, 14 February 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1r6b.png|left|200px]]
 
-
{{STRUCTURE_1r6b| PDB=1r6b | SCENE= }}
+
==High resolution crystal structure of ClpA==
-
 
+
<StructureSection load='1r6b' size='340' side='right'caption='[[1r6b]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
-
===High resolution crystal structure of ClpA===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[1r6b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R6B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R6B FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_15037248}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r6b OCA], [https://pdbe.org/1r6b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r6b RCSB], [https://www.ebi.ac.uk/pdbsum/1r6b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r6b ProSAT]</span></td></tr>
-
[[1r6b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R6B OCA].
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/CLPA_ECOLI CLPA_ECOLI] ATP-dependent specificity component of the ClpAP protease. It directs the protease to specific substrates. It has unfoldase activity. The primary function of the ClpA-ClpP complex appears to be the degradation of unfolded or abnormal proteins.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r6/1r6b_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1r6b ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
-
*[[Clp Protease|Clp Protease]]
+
*[[Heat Shock Protein structures|Heat Shock Protein structures]]
-
*[[Heat Shock Proteins|Heat Shock Proteins]]
+
__TOC__
-
 
+
</StructureSection>
-
==Reference==
+
-
<ref group="xtra">PMID:015037248</ref><references group="xtra"/>
+
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
-
[[Category: Esser, L.]]
+
[[Category: Large Structures]]
-
[[Category: Guo, F.]]
+
[[Category: Esser L]]
-
[[Category: Maurizi, M R.]]
+
[[Category: Guo F]]
-
[[Category: Singh, S K.]]
+
[[Category: Maurizi MR]]
-
[[Category: Xia, D.]]
+
[[Category: Singh SK]]
-
[[Category: Aaa+]]
+
[[Category: Xia D]]
-
[[Category: Binding mechanism]]
+
-
[[Category: Clpa]]
+
-
[[Category: Clp]]
+
-
[[Category: Crystal]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: N-terminal domain]]
+

Current revision

High resolution crystal structure of ClpA

PDB ID 1r6b

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1r6b"
Personal tools