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1r6c

From Proteopedia

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{{Seed}}
 
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[[Image:1r6c.png|left|200px]]
 
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==High resolution structure of ClpN==
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The line below this paragraph, containing "STRUCTURE_1r6c", creates the "Structure Box" on the page.
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<StructureSection load='1r6c' size='340' side='right'caption='[[1r6c]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1r6c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R6C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R6C FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r6c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r6c OCA], [https://pdbe.org/1r6c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r6c RCSB], [https://www.ebi.ac.uk/pdbsum/1r6c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r6c ProSAT]</span></td></tr>
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{{STRUCTURE_1r6c| PDB=1r6c | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CLPA_ECOLI CLPA_ECOLI] ATP-dependent specificity component of the ClpAP protease. It directs the protease to specific substrates. It has unfoldase activity. The primary function of the ClpA-ClpP complex appears to be the degradation of unfolded or abnormal proteins.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r6/1r6c_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1r6c ConSurf].
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<div style="clear:both"></div>
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===High resolution structure of ClpN===
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==See Also==
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*[[Heat Shock Protein structures|Heat Shock Protein structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_15037248}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 15037248 is the PubMed ID number.
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-->
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{{ABSTRACT_PUBMED_15037248}}
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==About this Structure==
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1R6C is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R6C OCA].
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==Reference==
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Crystallographic investigation of peptide binding sites in the N-domain of the ClpA chaperone., Xia D, Esser L, Singh SK, Guo F, Maurizi MR, J Struct Biol. 2004 Apr-May;146(1-2):166-79. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15037248 15037248]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Esser, L.]]
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[[Category: Esser L]]
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[[Category: Guo, F.]]
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[[Category: Guo F]]
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[[Category: Maurizi, M R.]]
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[[Category: Maurizi MR]]
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[[Category: Singh, S K.]]
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[[Category: Singh SK]]
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[[Category: Xia, D.]]
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[[Category: Xia D]]
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[[Category: Aaa+]]
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[[Category: Binding mechanism]]
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[[Category: Clpa]]
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[[Category: Clp]]
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[[Category: Crystal]]
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[[Category: N-terminal domain]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 10:42:13 2008''
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Current revision

High resolution structure of ClpN

PDB ID 1r6c

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