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1rna

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[[Image:1rna.gif|left|200px]]
 
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==CRYSTALLOGRAPHIC STRUCTURE OF AN RNA HELIX: [U(U-A)6A]2==
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The line below this paragraph, containing "STRUCTURE_1rna", creates the "Structure Box" on the page.
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<StructureSection load='1rna' size='340' side='right'caption='[[1rna]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1rna]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RNA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RNA FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rna FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rna OCA], [https://pdbe.org/1rna PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rna RCSB], [https://www.ebi.ac.uk/pdbsum/1rna PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rna ProSAT]</span></td></tr>
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{{STRUCTURE_1rna| PDB=1rna | SCENE= }}
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</table>
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__TOC__
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'''CRYSTALLOGRAPHIC STRUCTURE OF AN RNA HELIX: [U(U-A)6A]2'''
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Chevrier B]]
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==Overview==
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[[Category: De Bear JS]]
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The crystallographic structure of the synthetic oligoribonucleotide, U(UA)6A, has been solved at 2.25 A resolution. The crystallographic refinement permitted the identification of 91 solvent molecules, with a final agreement factor of 13%. The molecule is a dimer of 14 base-pairs and shows the typical features of an A-type helix. However, the presence of two kinks causes a divergence from a straight helix. The observed deformation, which is stabilized by a few hydrogen bonds in the crystal packing, could be due to the relatively high (35 degrees C) temperature of crystallization. The complete analysis of the structure is presented. It includes the stacking geometries, the backbone conformation and the solvation.
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[[Category: Dock-Bregeon AC]]
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[[Category: Gilham PT]]
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==About this Structure==
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[[Category: Gough GR]]
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RNA OCA].
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[[Category: Johnson J]]
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[[Category: Moras D]]
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==Reference==
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[[Category: Podjarny A]]
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Crystallographic structure of an RNA helix: [U(UA)6A]2., Dock-Bregeon AC, Chevrier B, Podjarny A, Johnson J, de Bear JS, Gough GR, Gilham PT, Moras D, J Mol Biol. 1989 Oct 5;209(3):459-74. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/2479753 2479753]
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[[Category: Bear, J S.De.]]
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[[Category: Chevrier, B.]]
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[[Category: Dock-Bregeon, A C.]]
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[[Category: Gilham, P T.]]
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[[Category: Gough, G R.]]
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[[Category: Johnson, J.]]
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[[Category: Moras, D.]]
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[[Category: Podjarny, A.]]
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[[Category: A-rna]]
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[[Category: Double helix]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 07:41:40 2008''
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Current revision

CRYSTALLOGRAPHIC STRUCTURE OF AN RNA HELIX: [U(U-A)6A]2

PDB ID 1rna

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