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1ryt

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(New page: 200px<br /><applet load="1ryt" size="450" color="white" frame="true" align="right" spinBox="true" caption="1ryt, resolution 2.1&Aring;" /> '''RUBRERYTHRIN'''<br />...)
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[[Image:1ryt.gif|left|200px]]<br /><applet load="1ryt" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1ryt, resolution 2.1&Aring;" />
 
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'''RUBRERYTHRIN'''<br />
 
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==Overview==
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==RUBRERYTHRIN==
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We have determined the structure of rubrerythrin, a non-haem iron protein, from the anaerobic sulphate-reducing bacterium, Desulfovibrio vulgaris, (Hildenborough), by X-ray crystallography. The structure reveals a, tetramer of two-domain subunits. Each subunit contains a four-helix bundle, surrounding a diiron-oxo site and a C-terminal rubredoxin-like FeS4, domain. The diiron-oxo site contains a larger number of carboxylate, ligands and a higher degree of solvent exposure than do those in other, diiron-oxo proteins. The four-helix bundle of rubrerythrin closely, resembles those of the ferritin and bacterioferritin subunits, suggesting, a relationship among these proteins-consistent with the recently, demonstrated ferroxidase activity of rubrerythrin.
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<StructureSection load='1ryt' size='340' side='right'caption='[[1ryt]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[1ryt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Desulfovibrio_vulgaris_str._Hildenborough Desulfovibrio vulgaris str. Hildenborough]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RYT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RYT FirstGlance]. <br>
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1RYT is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_vulgaris Desulfovibrio vulgaris] with FE as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1RYT OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ryt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ryt OCA], [https://pdbe.org/1ryt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ryt RCSB], [https://www.ebi.ac.uk/pdbsum/1ryt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ryt ProSAT]</span></td></tr>
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The structure of Desulfovibrio vulgaris rubrerythrin reveals a unique combination of rubredoxin-like FeS4 and ferritin-like diiron domains., deMare F, Kurtz DM Jr, Nordlund P, Nat Struct Biol. 1996 Jun;3(6):539-46. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8646540 8646540]
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</table>
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[[Category: Desulfovibrio vulgaris]]
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== Function ==
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[[Category: Single protein]]
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[https://www.uniprot.org/uniprot/RUBY_DESVH RUBY_DESVH] May provide oxidative stress protection via catalytic reduction of intracellular hydrogen peroxide (By similarity).
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[[Category: Demare, F.]]
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== Evolutionary Conservation ==
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[[Category: Kurtz, D.M.]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Nordlund, P.]]
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Check<jmol>
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[[Category: FE]]
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<jmolCheckbox>
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[[Category: electron transport]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ry/1ryt_consurf.spt"</scriptWhenChecked>
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[[Category: ferroxidase]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: iron]]
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 01:58:18 2007''
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ryt ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Desulfovibrio vulgaris str. Hildenborough]]
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[[Category: Large Structures]]
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[[Category: Demare F]]
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[[Category: Kurtz DM]]
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[[Category: Nordlund P]]

Current revision

RUBRERYTHRIN

PDB ID 1ryt

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