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1s0p

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{{Seed}}
 
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[[Image:1s0p.png|left|200px]]
 
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==Structure of the N-Terminal Domain of the Adenylyl Cyclase-Associated Protein (CAP) from Dictyostelium discoideum.==
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The line below this paragraph, containing "STRUCTURE_1s0p", creates the "Structure Box" on the page.
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<StructureSection load='1s0p' size='340' side='right'caption='[[1s0p]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1s0p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1pn1 1pn1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S0P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S0P FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_1s0p| PDB=1s0p | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s0p OCA], [https://pdbe.org/1s0p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s0p RCSB], [https://www.ebi.ac.uk/pdbsum/1s0p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s0p ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CAP_DICDI CAP_DICDI] May have a regulatory bifunctional role. Binds G-actin and PIP2. Involved in microfilament reorganization near the plasma membrane in a PIP2-regulated manner.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/s0/1s0p_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1s0p ConSurf].
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<div style="clear:both"></div>
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===Structure of the N-Terminal Domain of the Adenylyl Cyclase-Associated Protein (CAP) from Dictyostelium discoideum.===
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==See Also==
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*[[3D Adenylyl cyclase 3D structures|3D Adenylyl cyclase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12962635}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 12962635 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12962635}}
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==About this Structure==
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1S0P is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1pn1 1pn1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S0P OCA].
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==Reference==
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Structure of the N-terminal domain of the adenylyl cyclase-associated protein (CAP) from Dictyostelium discoideum., Ksiazek D, Brandstetter H, Israel L, Bourenkov GP, Katchalova G, Janssen KP, Bartunik HD, Noegel AA, Schleicher M, Holak TA, Structure. 2003 Sep;11(9):1171-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12962635 12962635]
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[[Category: Dictyostelium discoideum]]
[[Category: Dictyostelium discoideum]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Bartunik, H D.]]
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[[Category: Bartunik HD]]
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[[Category: Bourenkov, G P.]]
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[[Category: Bourenkov GP]]
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[[Category: Brandstetter, H.]]
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[[Category: Brandstetter H]]
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[[Category: Holak, T A.]]
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[[Category: Holak TA]]
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[[Category: Israel, L.]]
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[[Category: Israel L]]
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[[Category: Janssen, K P.]]
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[[Category: Janssen KP]]
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[[Category: Katchalova, G.]]
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[[Category: Katchalova G]]
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[[Category: Ksiazek, D.]]
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[[Category: Ksiazek D]]
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[[Category: Noegel, A A.]]
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[[Category: Noegel AA]]
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[[Category: Schleicher, M.]]
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[[Category: Schleicher M]]
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[[Category: Alpha helix bundle]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 19:36:58 2008''
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Current revision

Structure of the N-Terminal Domain of the Adenylyl Cyclase-Associated Protein (CAP) from Dictyostelium discoideum.

PDB ID 1s0p

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