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1s1f

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[[Image:1s1f.png|left|200px]]
 
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{{STRUCTURE_1s1f| PDB=1s1f | SCENE= }}
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==Crystal Structure of Streptomyces Coelicolor A3(2) CYP158A2 from antibiotic biosynthetic pathways==
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<StructureSection load='1s1f' size='340' side='right'caption='[[1s1f]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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===Crystal Structure of Streptomyces Coelicolor A3(2) CYP158A2 from antibiotic biosynthetic pathways===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1s1f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_coelicolor_A3(2) Streptomyces coelicolor A3(2)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S1F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S1F FirstGlance]. <br>
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{{ABSTRACT_PUBMED_15659395}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene>, <scene name='pdbligand=PIM:4-PHENYL-1H-IMIDAZOLE'>PIM</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s1f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s1f OCA], [https://pdbe.org/1s1f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s1f RCSB], [https://www.ebi.ac.uk/pdbsum/1s1f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s1f ProSAT]</span></td></tr>
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[[1s1f]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S1F OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/C1582_STRCO C1582_STRCO] Catalyze oxidative C-C coupling reaction to polymerize flaviolin and form highly conjugated pigments which protect the soil bacterium from deleterious effects of UV irradiation (three isomers of biflaviolin and one triflaviolin).<ref>PMID:15659395</ref> <ref>PMID:16239228</ref>
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<ref group="xtra">PMID:015659395</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Category: Streptomyces coelicolor]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Lamb, D C.]]
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Check<jmol>
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[[Category: Lei, L.]]
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<jmolCheckbox>
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[[Category: Podust, L M.]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/s1/1s1f_consurf.spt"</scriptWhenChecked>
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[[Category: Sundaramoorthy, M.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Waterman, M R.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Zhao, B.]]
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</jmolCheckbox>
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[[Category: Antibiotic biosynthesis]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1s1f ConSurf].
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[[Category: Cyp158a2]]
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<div style="clear:both"></div>
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[[Category: Cytochrome p450 oxidoreductase]]
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== References ==
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[[Category: Oxidoreductase]]
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<references/>
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[[Category: Streptomyce]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Lamb DC]]
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[[Category: Lei L]]
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[[Category: Podust LM]]
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[[Category: Sundaramoorthy M]]
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[[Category: Waterman MR]]
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[[Category: Zhao B]]

Current revision

Crystal Structure of Streptomyces Coelicolor A3(2) CYP158A2 from antibiotic biosynthetic pathways

PDB ID 1s1f

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