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1sd6

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{{Seed}}
 
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[[Image:1sd6.png|left|200px]]
 
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==Crystal Structure of Native MecI at 2.65 A==
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The line below this paragraph, containing "STRUCTURE_1sd6", creates the "Structure Box" on the page.
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<StructureSection load='1sd6' size='340' side='right'caption='[[1sd6]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1sd6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SD6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SD6 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sd6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sd6 OCA], [https://pdbe.org/1sd6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sd6 RCSB], [https://www.ebi.ac.uk/pdbsum/1sd6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sd6 ProSAT]</span></td></tr>
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{{STRUCTURE_1sd6| PDB=1sd6 | SCENE= }}
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</table>
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== Function ==
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===Crystal Structure of Native MecI at 2.65 A===
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[https://www.uniprot.org/uniprot/MECI_STAAU MECI_STAAU] Transcriptional repressor that constitutively blocks the transcription of the gene for the penicillin-binding protein MecA. Binds DNA as a dimer (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_15716455}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 15716455 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sd/1sd6_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_15716455}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sd6 ConSurf].
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1SD6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SD6 OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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Crystal structures of the BlaI repressor from Staphylococcus aureus and its complex with DNA: insights into transcriptional regulation of the bla and mec operons., Safo MK, Zhao Q, Ko TP, Musayev FN, Robinson H, Scarsdale N, Wang AH, Archer GL, J Bacteriol. 2005 Mar;187(5):1833-44. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15716455 15716455]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
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[[Category: Archer, G L.]]
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[[Category: Archer GL]]
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[[Category: Musayev, F N.]]
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[[Category: Musayev FN]]
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[[Category: Robinson, H.]]
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[[Category: Robinson H]]
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[[Category: Safo, M K.]]
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[[Category: Safo MK]]
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[[Category: Scarsdale, N.]]
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[[Category: Scarsdale N]]
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[[Category: Zhao, Q.]]
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[[Category: Zhao Q]]
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[[Category: B-lactam]]
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[[Category: Blai]]
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[[Category: Dna binding protein]]
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[[Category: Meci]]
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[[Category: Methicillin]]
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[[Category: Repressor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 13:23:47 2008''
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Current revision

Crystal Structure of Native MecI at 2.65 A

PDB ID 1sd6

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