1sqf

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{{Seed}}
 
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[[Image:1sqf.png|left|200px]]
 
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==The crystal structure of E. coli Fmu binary complex with S-Adenosylmethionine at 2.1 A resolution==
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The line below this paragraph, containing "STRUCTURE_1sqf", creates the "Structure Box" on the page.
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<StructureSection load='1sqf' size='340' side='right'caption='[[1sqf]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1sqf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SQF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SQF FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
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{{STRUCTURE_1sqf| PDB=1sqf | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sqf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sqf OCA], [https://pdbe.org/1sqf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sqf RCSB], [https://www.ebi.ac.uk/pdbsum/1sqf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sqf ProSAT]</span></td></tr>
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</table>
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===The crystal structure of E. coli Fmu binary complex with S-Adenosylmethionine at 2.1 A resolution===
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== Function ==
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[https://www.uniprot.org/uniprot/RSMB_ECOLI RSMB_ECOLI] Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.<ref>PMID:10194318</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_14656444}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 14656444 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sq/1sqf_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_14656444}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1SQF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SQF OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sqf ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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The first structure of an RNA m5C methyltransferase, Fmu, provides insight into catalytic mechanism and specific binding of RNA substrate., Foster PG, Nunes CR, Greene P, Moustakas D, Stroud RM, Structure. 2003 Dec;11(12):1609-20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14656444 14656444]
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<references/>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Foster, P G.]]
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[[Category: Foster PG]]
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[[Category: Greene, P.]]
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[[Category: Greene P]]
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[[Category: Moustakas, D.]]
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[[Category: Moustakas D]]
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[[Category: Nunes, C R.]]
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[[Category: Nunes CR]]
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[[Category: Stroud, R M.]]
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[[Category: Stroud RM]]
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[[Category: Methyltransferase-fold]]
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[[Category: Mixed beta sheet]]
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[[Category: Rna-binding domain]]
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[[Category: Rossmann-fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 12:45:03 2008''
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Current revision

The crystal structure of E. coli Fmu binary complex with S-Adenosylmethionine at 2.1 A resolution

PDB ID 1sqf

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