This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1st6

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "1st6" [edit=sysop:move=sysop])
Current revision (08:33, 14 February 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1st6.png|left|200px]]
 
-
<!--
+
==Crystal structure of a cytoskeletal protein==
-
The line below this paragraph, containing "STRUCTURE_1st6", creates the "Structure Box" on the page.
+
<StructureSection load='1st6' size='340' side='right'caption='[[1st6]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1st6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ST6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ST6 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1st6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1st6 OCA], [https://pdbe.org/1st6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1st6 RCSB], [https://www.ebi.ac.uk/pdbsum/1st6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1st6 ProSAT]</span></td></tr>
-
{{STRUCTURE_1st6| PDB=1st6 | SCENE= }}
+
</table>
-
 
+
== Function ==
-
===Crystal structure of a cytoskeletal protein===
+
[https://www.uniprot.org/uniprot/VINC_CHICK VINC_CHICK] Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.<ref>PMID:15229287</ref> <ref>PMID:20584916</ref> <ref>PMID:20086044</ref>
-
 
+
== Evolutionary Conservation ==
-
 
+
[[Image:Consurf_key_small.gif|200px|right]]
-
<!--
+
Check<jmol>
-
The line below this paragraph, {{ABSTRACT_PUBMED_15195105}}, adds the Publication Abstract to the page
+
<jmolCheckbox>
-
(as it appears on PubMed at http://www.pubmed.gov), where 15195105 is the PubMed ID number.
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/st/1st6_consurf.spt"</scriptWhenChecked>
-
-->
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
{{ABSTRACT_PUBMED_15195105}}
+
<text>to colour the structure by Evolutionary Conservation</text>
-
 
+
</jmolCheckbox>
-
==About this Structure==
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1st6 ConSurf].
-
[[1st6]] is a 1 chain structure of [[Vinculin]] with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ST6 OCA].
+
<div style="clear:both"></div>
==See Also==
==See Also==
*[[Vinculin|Vinculin]]
*[[Vinculin|Vinculin]]
-
 
+
== References ==
-
==Reference==
+
<references/>
-
<ref group="xtra">PMID:015195105</ref><ref group="xtra">PMID:018980387</ref><references group="xtra"/>
+
__TOC__
 +
</StructureSection>
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
-
[[Category: Bakolitsa, C.]]
+
[[Category: Large Structures]]
-
[[Category: Liddington, R C.]]
+
[[Category: Bakolitsa C]]
-
[[Category: Cell adhesion]]
+
[[Category: Liddington RC]]
-
[[Category: Up-down bundle]]
+

Current revision

Crystal structure of a cytoskeletal protein

PDB ID 1st6

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools