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1sx8

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{{Seed}}
 
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[[Image:1sx8.png|left|200px]]
 
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==EcoRV bound to cognate DNA and Mn2+==
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The line below this paragraph, containing "STRUCTURE_1sx8", creates the "Structure Box" on the page.
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<StructureSection load='1sx8' size='340' side='right'caption='[[1sx8]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1sx8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SX8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SX8 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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{{STRUCTURE_1sx8| PDB=1sx8 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sx8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sx8 OCA], [https://pdbe.org/1sx8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sx8 RCSB], [https://www.ebi.ac.uk/pdbsum/1sx8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sx8 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/T2E5_ECOLX T2E5_ECOLX] Recognizes the double-stranded sequence GATATC and cleaves after T-3.
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===EcoRV bound to cognate DNA and Mn2+===
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==See Also==
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*[[Endonuclease 3D structures|Endonuclease 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_15170321}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 15170321 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15170321}}
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==About this Structure==
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1SX8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SX8 OCA].
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==Reference==
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DNA cleavage by EcoRV endonuclease: two metal ions in three metal ion binding sites., Horton NC, Perona JJ, Biochemistry. 2004 Jun 8;43(22):6841-57. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15170321 15170321]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Type II site-specific deoxyribonuclease]]
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[[Category: Horton NC]]
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[[Category: Horton, N C.]]
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[[Category: Perona JJ]]
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[[Category: Perona, J J.]]
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[[Category: Hydrolase/dna]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 21:34:06 2008''
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Current revision

EcoRV bound to cognate DNA and Mn2+

PDB ID 1sx8

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