This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1t5s

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:36, 14 February 2024) (edit) (undo)
 
(12 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1t5s.png|left|200px]]
 
-
<!--
+
==Structure of the (SR)Ca2+-ATPase Ca2-E1-AMPPCP form==
-
The line below this paragraph, containing "STRUCTURE_1t5s", creates the "Structure Box" on the page.
+
<StructureSection load='1t5s' size='340' side='right'caption='[[1t5s]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1t5s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T5S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T5S FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-
{{STRUCTURE_1t5s| PDB=1t5s | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t5s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t5s OCA], [https://pdbe.org/1t5s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t5s RCSB], [https://www.ebi.ac.uk/pdbsum/1t5s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t5s ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/AT2A1_RABIT AT2A1_RABIT] This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction (By similarity).
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t5/1t5s_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1t5s ConSurf].
 +
<div style="clear:both"></div>
-
===Structure of the (SR)Ca2+-ATPase Ca2-E1-AMPPCP form===
+
==See Also==
-
 
+
*[[ATPase 3D structures|ATPase 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_15192230}}, adds the Publication Abstract to the page
+
[[Category: Large Structures]]
-
(as it appears on PubMed at http://www.pubmed.gov), where 15192230 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_15192230}}
+
-
 
+
-
==About this Structure==
+
-
1T5S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T5S OCA].
+
-
 
+
-
==Reference==
+
-
Phosphoryl transfer and calcium ion occlusion in the calcium pump., Sorensen TL, Moller JV, Nissen P, Science. 2004 Jun 11;304(5677):1672-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15192230 15192230]
+
-
[[Category: Calcium-transporting ATPase]]
+
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
-
[[Category: Single protein]]
+
[[Category: Moller JV]]
-
[[Category: Moller, J V.]]
+
[[Category: Nissen P]]
-
[[Category: Nissen, P.]]
+
[[Category: Sorensen TL-M]]
-
[[Category: Sorensen, T L.M.]]
+
-
[[Category: Calcium pump]]
+
-
[[Category: Catalytic mechanism]]
+
-
[[Category: Domain movement]]
+
-
[[Category: Membrane protein]]
+
-
[[Category: Nonhydrolyzable atp analog]]
+
-
[[Category: Nucleotide binding]]
+
-
[[Category: Phosphorylation]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 20:03:17 2008''
+

Current revision

Structure of the (SR)Ca2+-ATPase Ca2-E1-AMPPCP form

PDB ID 1t5s

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1t5s"
Personal tools