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1thj

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{{Seed}}
 
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[[Image:1thj.png|left|200px]]
 
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==CARBONIC ANHYDRASE FROM METHANOSARCINA==
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The line below this paragraph, containing "STRUCTURE_1thj", creates the "Structure Box" on the page.
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<StructureSection load='1thj' size='340' side='right'caption='[[1thj]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1thj]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanosarcina_thermophila Methanosarcina thermophila]. The January 2004 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Carbonic Anhydrase'' by Shuchismita Dutta and David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2004_1 10.2210/rcsb_pdb/mom_2004_1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1THJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1THJ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_1thj| PDB=1thj | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1thj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1thj OCA], [https://pdbe.org/1thj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1thj RCSB], [https://www.ebi.ac.uk/pdbsum/1thj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1thj ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CAH_METTT CAH_METTT] Reversible hydration of carbon dioxide. Important for growth on acetate (PubMed:8041719). As a probably extracellular enzyme, it may support a H(+)/CH(3)COO(-) symport mechanism and/or conversion of CO(2) to HCO(3)(-), removing excess CO(2) produced by growth on acetate (Probable).<ref>PMID:8041719</ref> <ref>PMID:10924115</ref> <ref>PMID:8041719</ref> <ref>PMID:8665839</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/th/1thj_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1thj ConSurf].
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<div style="clear:both"></div>
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===CARBONIC ANHYDRASE FROM METHANOSARCINA===
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==See Also==
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*[[Carbonic anhydrase 3D structures|Carbonic anhydrase 3D structures]]
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_8665839}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 8665839 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_8665839}}
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==About this Structure==
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1THJ is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Methanosarcina_thermophila Methanosarcina thermophila]. The January 2004 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Carbonic Anhydrase'' by Shuchismita Dutta and David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2004_1 10.2210/rcsb_pdb/mom_2004_1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1THJ OCA].
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==Reference==
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<ref group="xtra">PMID:8665839</ref><references group="xtra"/>
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[[Category: Carbonate dehydratase]]
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[[Category: Carbonic Anhydrase]]
[[Category: Carbonic Anhydrase]]
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[[Category: Large Structures]]
[[Category: Methanosarcina thermophila]]
[[Category: Methanosarcina thermophila]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Kisker, C.]]
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[[Category: Kisker C]]
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[[Category: Rees, D C.]]
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[[Category: Rees DC]]
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[[Category: Schindelin, H.]]
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[[Category: Schindelin H]]
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[[Category: Carbonic anhydrase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 21 09:24:44 2010''
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Current revision

CARBONIC ANHYDRASE FROM METHANOSARCINA

PDB ID 1thj

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