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1tpv

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[[Image:1tpv.png|left|200px]]
 
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{{STRUCTURE_1tpv| PDB=1tpv | SCENE= }}
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==S96P CHANGE IS A SECOND-SITE SUPPRESSOR FOR H95N SLUGGISH MUTANT TRIOSEPHOSPHATE ISOMERASE==
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<StructureSection load='1tpv' size='340' side='right'caption='[[1tpv]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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===S96P CHANGE IS A SECOND-SITE SUPPRESSOR FOR H95N SLUGGISH MUTANT TRIOSEPHOSPHATE ISOMERASE===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1tpv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TPV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TPV FirstGlance]. <br>
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{{ABSTRACT_PUBMED_8952501}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PGH:PHOSPHOGLYCOLOHYDROXAMIC+ACID'>PGH</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tpv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tpv OCA], [https://pdbe.org/1tpv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tpv RCSB], [https://www.ebi.ac.uk/pdbsum/1tpv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tpv ProSAT]</span></td></tr>
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[[1tpv]] is a 2 chain structure of [[TIM test]] and [[Triose Phosphate Isomerase]] with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TPV OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TPIS_CHICK TPIS_CHICK]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tp/1tpv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tpv ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[TIM test|TIM test]]
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*[[Triose phosphate isomerase 3D structures|Triose phosphate isomerase 3D structures]]
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*[[Triose Phosphate Isomerase|Triose Phosphate Isomerase]]
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__TOC__
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:008952501</ref><references group="xtra"/>
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[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
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[[Category: Triose-phosphate isomerase]]
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[[Category: Large Structures]]
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[[Category: Knowles, J R.]]
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[[Category: Knowles JR]]
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[[Category: Komives, E A.]]
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[[Category: Komives EA]]
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[[Category: Liu, K D.]]
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[[Category: Liu KD]]
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[[Category: Narayana, N.]]
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[[Category: Narayana N]]
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[[Category: Petsko, G A.]]
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[[Category: Petsko GA]]
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[[Category: Ringe, D.]]
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[[Category: Ringe D]]
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[[Category: Stock, A M.]]
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[[Category: Stock AM]]
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[[Category: Sugio, S.]]
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[[Category: Sugio S]]
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[[Category: Xuong, Ng H.]]
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[[Category: Xuong NgH]]
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[[Category: Zhang, Z.]]
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[[Category: Zhang Z]]

Current revision

S96P CHANGE IS A SECOND-SITE SUPPRESSOR FOR H95N SLUGGISH MUTANT TRIOSEPHOSPHATE ISOMERASE

PDB ID 1tpv

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