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1trj

From Proteopedia

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{{Seed}}
 
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[[Image:1trj.png|left|200px]]
 
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<!--
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==Homology Model of Yeast RACK1 Protein fitted into 11.7A cryo-EM map of Yeast 80S Ribosome==
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The line below this paragraph, containing "STRUCTURE_1trj", creates the "Structure Box" on the page.
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<SX load='1trj' size='340' side='right' viewer='molstar' caption='[[1trj]], [[Resolution|resolution]] 11.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1trj]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TRJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TRJ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 11.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1trj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1trj OCA], [https://pdbe.org/1trj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1trj RCSB], [https://www.ebi.ac.uk/pdbsum/1trj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1trj ProSAT]</span></td></tr>
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{{STRUCTURE_1trj| PDB=1trj | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GBLP_YEAST GBLP_YEAST] Located at the head of the 40S ribosomal subunit in the vicinity of the mRNA exit channel, it serves as a scaffold protein that can recruit other proteins to the ribosome. Involved in the negative regulation of translation of a specific subset of proteins.<ref>PMID:15340087</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tr/1trj_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1trj ConSurf].
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<div style="clear:both"></div>
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===Homology Model of Yeast RACK1 Protein fitted into 11.7A cryo-EM map of Yeast 80S Ribosome===
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==See Also==
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*[[3D sructureseceptor for activated protein kinase C 1|3D sructureseceptor for activated protein kinase C 1]]
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== References ==
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<!--
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_15334071}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 15334071 is the PubMed ID number.
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</SX>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_15334071}}
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==About this Structure==
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1TRJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TRJ OCA].
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==Reference==
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Identification of the versatile scaffold protein RACK1 on the eukaryotic ribosome by cryo-EM., Sengupta J, Nilsson J, Gursky R, Spahn CM, Nissen P, Frank J, Nat Struct Mol Biol. 2004 Oct;11(10):957-62. Epub 2004 Aug 29. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15334071 15334071]
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[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Single protein]]
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[[Category: Frank J]]
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[[Category: Frank, J.]]
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[[Category: Gursky R]]
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[[Category: Gursky, R.]]
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[[Category: Nilsson J]]
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[[Category: Nilsson, J.]]
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[[Category: Nissen P]]
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[[Category: Nissen, P.]]
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[[Category: Sengupta J]]
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[[Category: Sengupta, J.]]
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[[Category: Spahn CM]]
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[[Category: Spahn, C M.]]
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[[Category: Cryo-electron microscopy]]
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[[Category: Homology model]]
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[[Category: Rack1]]
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[[Category: Ribosome]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 19:39:53 2008''
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Current revision

Homology Model of Yeast RACK1 Protein fitted into 11.7A cryo-EM map of Yeast 80S Ribosome

1trj, resolution 11.70Å

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