This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.




1tsw

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "1tsw" [edit=sysop:move=sysop])
Current revision (08:41, 14 February 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1tsw.png|left|200px]]
 
-
<!--
+
==THYMIDYLATE SYNTHASE R179A MUTANT==
-
The line below this paragraph, containing "STRUCTURE_1tsw", creates the "Structure Box" on the page.
+
<StructureSection load='1tsw' size='340' side='right'caption='[[1tsw]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1tsw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lacticaseibacillus_casei Lacticaseibacillus casei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TSW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TSW FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-
{{STRUCTURE_1tsw| PDB=1tsw | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tsw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tsw OCA], [https://pdbe.org/1tsw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tsw RCSB], [https://www.ebi.ac.uk/pdbsum/1tsw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tsw ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/TYSY_LACCA TYSY_LACCA] Provides the sole de novo source of dTMP for DNA biosynthesis.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ts/1tsw_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tsw ConSurf].
 +
<div style="clear:both"></div>
-
===THYMIDYLATE SYNTHASE R179A MUTANT===
+
==See Also==
-
 
+
*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_9053905}}, adds the Publication Abstract to the page
+
[[Category: Lacticaseibacillus casei]]
-
(as it appears on PubMed at http://www.pubmed.gov), where 9053905 is the PubMed ID number.
+
[[Category: Large Structures]]
-
-->
+
[[Category: Finer-Moore J]]
-
{{ABSTRACT_PUBMED_9053905}}
+
[[Category: Stroud RM]]
-
 
+
-
==About this Structure==
+
-
[[1tsw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lactobacillus_casei Lactobacillus casei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TSW OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:009053905</ref><references group="xtra"/>
+
-
[[Category: Lactobacillus casei]]
+
-
[[Category: Thymidylate synthase]]
+
-
[[Category: Finer-Moore, J.]]
+
-
[[Category: Stroud, R M.]]
+
-
[[Category: Methyltransferase]]
+
-
[[Category: Nucleotide biosynthesis]]
+
-
[[Category: Transferase]]
+

Current revision

THYMIDYLATE SYNTHASE R179A MUTANT

PDB ID 1tsw

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1tsw"
Personal tools