This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1tt4
From Proteopedia
(Difference between revisions)
| (15 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:1tt4.jpg|left|200px]]<br /><applet load="1tt4" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1tt4, resolution 2.801Å" /> | ||
| - | '''Structure of NP459575, a predicted glutathione synthase from Salmonella typhimurium'''<br /> | ||
| - | == | + | ==Structure of NP459575, a predicted glutathione synthase from Salmonella typhimurium== |
| - | + | <StructureSection load='1tt4' size='340' side='right'caption='[[1tt4]], [[Resolution|resolution]] 2.80Å' scene=''> | |
| - | [ | + | == Structural highlights == |
| - | [ | + | <table><tr><td colspan='2'>[[1tt4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TT4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TT4 FirstGlance]. <br> |
| - | [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.801Å</td></tr> |
| - | [ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tt4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tt4 OCA], [https://pdbe.org/1tt4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tt4 RCSB], [https://www.ebi.ac.uk/pdbsum/1tt4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tt4 ProSAT], [https://www.topsan.org/Proteins/MCSG/1tt4 TOPSAN]</span></td></tr> |
| - | [ | + | </table> |
| - | [[ | + | == Function == |
| - | [ | + | [https://www.uniprot.org/uniprot/GCS2_SALTY GCS2_SALTY] ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.[HAMAP-Rule:MF_01609] |
| - | [[ | + | == Evolutionary Conservation == |
| - | [ | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [[Category: | + | Check<jmol> |
| - | [[Category: | + | <jmolCheckbox> |
| - | [[Category: | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tt/1tt4_consurf.spt"</scriptWhenChecked> |
| - | [[Category: | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | [[Category: | + | <text>to colour the structure by Evolutionary Conservation</text> |
| - | + | </jmolCheckbox> | |
| - | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tt4 ConSurf]. | |
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]] | ||
| + | [[Category: Anderson WF]] | ||
| + | [[Category: Miller DJ]] | ||
| + | [[Category: Shuvalova L]] | ||
Current revision
Structure of NP459575, a predicted glutathione synthase from Salmonella typhimurium
| |||||||||||
