This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1tuu

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:42, 14 February 2024) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1tuu.png|left|200px]]
 
-
<!--
+
==Acetate Kinase crystallized with ATPgS==
-
The line below this paragraph, containing "STRUCTURE_1tuu", creates the "Structure Box" on the page.
+
<StructureSection load='1tuu' size='340' side='right'caption='[[1tuu]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1tuu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanosarcina_thermophila Methanosarcina thermophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TUU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TUU FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene>, <scene name='pdbligand=PIS:TRIHYDROGEN+THIODIPHOSPHATE'>PIS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
{{STRUCTURE_1tuu| PDB=1tuu | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tuu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tuu OCA], [https://pdbe.org/1tuu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tuu RCSB], [https://www.ebi.ac.uk/pdbsum/1tuu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tuu ProSAT]</span></td></tr>
-
 
+
</table>
-
===Acetate Kinase crystallized with ATPgS===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/ACKA_METTE ACKA_METTE] Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. Can also phosphorylate propionate, but has very low activity toward butyrate.<ref>PMID:15774882</ref>
-
 
+
== Evolutionary Conservation ==
-
<!--
+
[[Image:Consurf_key_small.gif|200px|right]]
-
The line below this paragraph, {{ABSTRACT_PUBMED_15647264}}, adds the Publication Abstract to the page
+
Check<jmol>
-
(as it appears on PubMed at http://www.pubmed.gov), where 15647264 is the PubMed ID number.
+
<jmolCheckbox>
-
-->
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tu/1tuu_consurf.spt"</scriptWhenChecked>
-
{{ABSTRACT_PUBMED_15647264}}
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
 
+
<text>to colour the structure by Evolutionary Conservation</text>
-
==About this Structure==
+
</jmolCheckbox>
-
1TUU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanosarcina_thermophila Methanosarcina thermophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TUU OCA].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tuu ConSurf].
-
 
+
<div style="clear:both"></div>
-
==Reference==
+
== References ==
-
Structural and kinetic analyses of arginine residues in the active site of the acetate kinase from Methanosarcina thermophila., Gorrell A, Lawrence SH, Ferry JG, J Biol Chem. 2005 Mar 18;280(11):10731-42. Epub 2005 Jan 12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15647264 15647264]
+
<references/>
-
[[Category: Acetate kinase]]
+
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Methanosarcina thermophila]]
[[Category: Methanosarcina thermophila]]
-
[[Category: Single protein]]
+
[[Category: Ferry JG]]
-
[[Category: Ferry, J G.]]
+
[[Category: Gorrell A]]
-
[[Category: Gorrell, A.]]
+
[[Category: Lawrence SH]]
-
[[Category: Lawrence, S H.]]
+
-
[[Category: Alpha/beta]]
+
-
[[Category: Two similar domain]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 11:49:13 2008''
+

Current revision

Acetate Kinase crystallized with ATPgS

PDB ID 1tuu

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools