This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1u0c

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:43, 14 February 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1u0c.png|left|200px]]
 
-
{{STRUCTURE_1u0c| PDB=1u0c | SCENE= }}
+
==Y33C Mutant of Homing endonuclease I-CreI==
-
 
+
<StructureSection load='1u0c' size='340' side='right'caption='[[1u0c]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-
===Y33C Mutant of Homing endonuclease I-CreI===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[1u0c]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U0C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U0C FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_15313605}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u0c OCA], [https://pdbe.org/1u0c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u0c RCSB], [https://www.ebi.ac.uk/pdbsum/1u0c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u0c ProSAT]</span></td></tr>
-
[[1u0c]] is a 4 chain structure of [[Endonuclease]] with sequence from [http://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U0C OCA].
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/DNE1_CHLRE DNE1_CHLRE] Endonuclease involved in group I intron homing. Recognizes and cleaves a 19-24 bp palindromic DNA site.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u0/1u0c_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u0c ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
-
*[[Endonuclease|Endonuclease]]
+
*[[Endonuclease 3D structures|Endonuclease 3D structures]]
-
 
+
__TOC__
-
==Reference==
+
</StructureSection>
-
<ref group="xtra">PMID:015313605</ref><references group="xtra"/>
+
[[Category: Chlamydomonas reinhardtii]]
[[Category: Chlamydomonas reinhardtii]]
-
[[Category: Bruett, A.]]
+
[[Category: Large Structures]]
-
[[Category: Chadsey, M.]]
+
[[Category: Bruett A]]
-
[[Category: Engel, A.]]
+
[[Category: Chadsey M]]
-
[[Category: Fauce, S.]]
+
[[Category: Engel A]]
-
[[Category: Monnat, R.]]
+
[[Category: Fauce S]]
-
[[Category: Seligman, L M.]]
+
[[Category: Monnat R]]
-
[[Category: Stoddard, B L.]]
+
[[Category: Seligman LM]]
-
[[Category: Sussman, D.]]
+
[[Category: Stoddard BL]]
-
[[Category: Dna endonuclease i-crei]]
+
[[Category: Sussman D]]
-
[[Category: Hydrolase-dna complex]]
+
-
[[Category: Protein/dna]]
+

Current revision

Y33C Mutant of Homing endonuclease I-CreI

PDB ID 1u0c

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools