1u6z

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[[Image:1u6z.gif|left|200px]]
 
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{{Structure
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==Structure of an E. coli Exopolyphosphatase: Insight into the processive hydrolysis of polyphosphate and its regulation==
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|PDB= 1u6z |SIZE=350|CAPTION= <scene name='initialview01'>1u6z</scene>, resolution 1.90&Aring;
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<StructureSection load='1u6z' size='340' side='right'caption='[[1u6z]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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<table><tr><td colspan='2'>[[1u6z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U6Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U6Z FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Exopolyphosphatase Exopolyphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.11 3.6.1.11] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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|GENE= ppx ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u6z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u6z OCA], [https://pdbe.org/1u6z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u6z RCSB], [https://www.ebi.ac.uk/pdbsum/1u6z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u6z ProSAT]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u6z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u6z OCA], [http://www.ebi.ac.uk/pdbsum/1u6z PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1u6z RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/PPX_ECOLI PPX_ECOLI] Degradation of inorganic polyphosphates. Orthophosphate is released progressively from the ends of polyphosphate of circa 500 residues long, while chains of circa 15 residues compete poorly with polyphosphate as substrate.
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== Evolutionary Conservation ==
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'''Structure of an E. coli Exopolyphosphatase: Insight into the processive hydrolysis of polyphosphate and its regulation'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u6/1u6z_consurf.spt"</scriptWhenChecked>
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1U6Z is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U6Z OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u6z ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Exopolyphosphatase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Alvarado J]]
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[[Category: Alvarado, J.]]
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[[Category: Hasson MS]]
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[[Category: Hasson, M S.]]
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[[Category: Sanders DA]]
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[[Category: Sanders, D A.]]
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[[Category: actin) superfamily]]
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[[Category: alpha/beta protein]]
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[[Category: askha (acetate and sugar kinase]]
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[[Category: hd metal dependent phosphohydrolase superfamily]]
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[[Category: hsc70]]
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[[Category: polyphosphate]]
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[[Category: twenty-nine sulfate]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:06:11 2008''
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Current revision

Structure of an E. coli Exopolyphosphatase: Insight into the processive hydrolysis of polyphosphate and its regulation

PDB ID 1u6z

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