This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1u9s

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:44, 14 February 2024) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Crystal structure of the specificity domain of Ribonuclease P of the A-type==
==Crystal structure of the specificity domain of Ribonuclease P of the A-type==
-
<StructureSection load='1u9s' size='340' side='right' caption='[[1u9s]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
+
<StructureSection load='1u9s' size='340' side='right'caption='[[1u9s]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1u9s]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U9S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1U9S FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1u9s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U9S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U9S FirstGlance]. <br>
-
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BA:BARIUM+ION'>BA</scene><br>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
-
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1nbs|1nbs]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BA:BARIUM+ION'>BA</scene></td></tr>
-
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u9s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u9s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1u9s RCSB], [http://www.ebi.ac.uk/pdbsum/1u9s PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u9s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u9s OCA], [https://pdbe.org/1u9s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u9s RCSB], [https://www.ebi.ac.uk/pdbsum/1u9s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u9s ProSAT]</span></td></tr>
-
<table>
+
</table>
-
<div style="background-color:#fffaf0;">
+
-
== Publication Abstract from PubMed ==
+
-
Large RNA molecules, such as ribozymes, fold with well-defined tertiary structures that are important for their activity. There are many instances of ribozymes with identical function but differences in their secondary structures, suggesting alternative tertiary folds. Here, we report a crystal structure of the 161-nucleotide specificity domain of an A-type ribonuclease P that differs in secondary and tertiary structure from the specificity domain of a B-type molecule. Despite the differences, the cores of the domains have similar three-dimensional structure. Remarkably, the similar geometry of the cores is stabilized by a different set of interactions involving distinct auxiliary elements.
+
-
 
+
-
Basis for structural diversity in homologous RNAs.,Krasilnikov AS, Xiao Y, Pan T, Mondragon A Science. 2004 Oct 1;306(5693):104-7. PMID:15459389<ref>PMID:15459389</ref>
+
-
 
+
-
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+
-
</div>
+
==See Also==
==See Also==
-
*[[Ribonuclease|Ribonuclease]]
+
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
-
== References ==
+
-
<references/>
+
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Krasilnikov, A S.]]
+
[[Category: Large Structures]]
-
[[Category: Mondragon, A.]]
+
-
[[Category: Pan, T.]]
+
-
[[Category: Xiao, Y.]]
+
-
[[Category: P rna]]
+
-
[[Category: Pre-trna]]
+
-
[[Category: Ribonuclease p rna]]
+
-
[[Category: Ribozyme]]
+
-
[[Category: Rna]]
+
-
[[Category: Rnase p]]
+
-
[[Category: S-domain]]
+
-
[[Category: Specificity domain]]
+
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
-
[[Category: Trna]]
+
[[Category: Krasilnikov AS]]
 +
[[Category: Mondragon A]]
 +
[[Category: Pan T]]
 +
[[Category: Xiao Y]]

Current revision

Crystal structure of the specificity domain of Ribonuclease P of the A-type

PDB ID 1u9s

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1u9s"
Personal tools