This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1vie

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:46, 14 February 2024) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1vie.png|left|200px]]
 
-
<!--
+
==STRUCTURE OF DIHYDROFOLATE REDUCTASE==
-
The line below this paragraph, containing "STRUCTURE_1vie", creates the "Structure Box" on the page.
+
<StructureSection load='1vie' size='340' side='right'caption='[[1vie]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1vie]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VIE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VIE FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vie FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vie OCA], [https://pdbe.org/1vie PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vie RCSB], [https://www.ebi.ac.uk/pdbsum/1vie PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vie ProSAT]</span></td></tr>
-
{{STRUCTURE_1vie| PDB=1vie | SCENE= }}
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/DYR21_ECOLX DYR21_ECOLX] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
-
===STRUCTURE OF DIHYDROFOLATE REDUCTASE===
+
==See Also==
-
 
+
*[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_7583655}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 7583655 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_7583655}}
+
-
 
+
-
==About this Structure==
+
-
1VIE is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VIE OCA].
+
-
 
+
-
==Reference==
+
-
A plasmid-encoded dihydrofolate reductase from trimethoprim-resistant bacteria has a novel D2-symmetric active site., Narayana N, Matthews DA, Howell EE, Nguyen-huu X, Nat Struct Biol. 1995 Nov;2(11):1018-25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7583655 7583655]
+
-
[[Category: Dihydrofolate reductase]]
+
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Howell, E E.]]
+
[[Category: Howell EE]]
-
[[Category: Matthews, D A.]]
+
[[Category: Matthews DA]]
-
[[Category: Narayana, N.]]
+
[[Category: Narayana N]]
-
[[Category: Xuong, N H.]]
+
[[Category: Xuong N-H]]
-
[[Category: Methotrexate resistance]]
+
-
[[Category: Nadp]]
+
-
[[Category: One-carbon metabolism]]
+
-
[[Category: Oxidoreductase]]
+
-
[[Category: Plasmid]]
+
-
[[Category: Trimethoprim resistance]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 05:42:11 2008''
+

Current revision

STRUCTURE OF DIHYDROFOLATE REDUCTASE

PDB ID 1vie

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1vie"
Personal tools