This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1vza

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:47, 14 February 2024) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1vza.png|left|200px]]
 
-
<!--
+
==THYMIDYLATE SYNTHASE E60D MUTANT BINARY COMPLEX WITH 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (DUMP)==
-
The line below this paragraph, containing "STRUCTURE_1vza", creates the "Structure Box" on the page.
+
<StructureSection load='1vza' size='340' side='right'caption='[[1vza]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1vza]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lacticaseibacillus_casei Lacticaseibacillus casei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VZA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VZA FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr>
-
{{STRUCTURE_1vza| PDB=1vza | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vza FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vza OCA], [https://pdbe.org/1vza PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vza RCSB], [https://www.ebi.ac.uk/pdbsum/1vza PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vza ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/TYSY_LACCA TYSY_LACCA] Provides the sole de novo source of dTMP for DNA biosynthesis.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vz/1vza_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vza ConSurf].
 +
<div style="clear:both"></div>
-
===THYMIDYLATE SYNTHASE E60D MUTANT BINARY COMPLEX WITH 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (DUMP)===
+
==See Also==
-
 
+
*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_8568895}}, adds the Publication Abstract to the page
+
[[Category: Lacticaseibacillus casei]]
-
(as it appears on PubMed at http://www.pubmed.gov), where 8568895 is the PubMed ID number.
+
[[Category: Large Structures]]
-
-->
+
[[Category: Birdsall DL]]
-
{{ABSTRACT_PUBMED_8568895}}
+
[[Category: Finer-Moore J]]
-
 
+
[[Category: Stroud RM]]
-
==About this Structure==
+
-
1VZA is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Lactobacillus_casei Lactobacillus casei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VZA OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:8568895</ref><references group="xtra"/>
+
-
[[Category: Lactobacillus casei]]
+
-
[[Category: Thymidylate synthase]]
+
-
[[Category: Birdsall, D L.]]
+
-
[[Category: Finer-Moore, J.]]
+
-
[[Category: Stroud, R M.]]
+
-
[[Category: Methyltransferase]]
+
-
[[Category: Nucleotide synthase]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 20:59:00 2009''
+

Current revision

THYMIDYLATE SYNTHASE E60D MUTANT BINARY COMPLEX WITH 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (DUMP)

PDB ID 1vza

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1vza"
Personal tools