1vzb

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:47, 14 February 2024) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1vzb.png|left|200px]]
 
-
{{STRUCTURE_1vzb| PDB=1vzb | SCENE= }}
+
==L. CASEI THYMIDYLATE SYNTHASE MUTANT E60Q BINARY COMPLEX WITH DUMP==
-
 
+
<StructureSection load='1vzb' size='340' side='right'caption='[[1vzb]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-
===L. CASEI THYMIDYLATE SYNTHASE MUTANT E60Q BINARY COMPLEX WITH DUMP===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[1vzb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lacticaseibacillus_casei Lacticaseibacillus casei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VZB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VZB FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_9613841}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vzb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vzb OCA], [https://pdbe.org/1vzb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vzb RCSB], [https://www.ebi.ac.uk/pdbsum/1vzb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vzb ProSAT]</span></td></tr>
-
[[1vzb]] is a 1 chain structure of [[Thymidylate synthase]] with sequence from [http://en.wikipedia.org/wiki/Lactobacillus_casei Lactobacillus casei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VZB OCA].
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/TYSY_LACCA TYSY_LACCA] Provides the sole de novo source of dTMP for DNA biosynthesis.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vz/1vzb_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vzb ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
-
*[[Thymidylate synthase|Thymidylate synthase]]
+
*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]]
-
 
+
__TOC__
-
==Reference==
+
</StructureSection>
-
<ref group="xtra">PMID:009613841</ref><references group="xtra"/>
+
[[Category: Lacticaseibacillus casei]]
-
[[Category: Lactobacillus casei]]
+
[[Category: Large Structures]]
-
[[Category: Thymidylate synthase]]
+
[[Category: Birdsall DL]]
-
[[Category: Birdsall, D L.]]
+
[[Category: Finer-Moore J]]
-
[[Category: Finer-Moore, J.]]
+
[[Category: Stroud RM]]
-
[[Category: Stroud, R M.]]
+
-
[[Category: Methyltransferase]]
+
-
[[Category: Nucleotide synthase]]
+

Current revision

L. CASEI THYMIDYLATE SYNTHASE MUTANT E60Q BINARY COMPLEX WITH DUMP

PDB ID 1vzb

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1vzb"
Personal tools