This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1xen

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:49, 14 February 2024) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1xen.png|left|200px]]
 
-
<!--
+
==High Resolution Crystal Structure of Escherichia coli Iron- Peptide Deformylase Bound To Formate==
-
The line below this paragraph, containing "STRUCTURE_1xen", creates the "Structure Box" on the page.
+
<StructureSection load='1xen' size='340' side='right'caption='[[1xen]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1xen]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_BL21(DE3) Escherichia coli BL21(DE3)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XEN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XEN FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene></td></tr>
-
{{STRUCTURE_1xen| PDB=1xen | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xen OCA], [https://pdbe.org/1xen PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xen RCSB], [https://www.ebi.ac.uk/pdbsum/1xen PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xen ProSAT]</span></td></tr>
-
 
+
</table>
-
===High Resolution Crystal Structure of Escherichia coli Iron- Peptide Deformylase Bound To Formate===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/DEF_ECOLI DEF_ECOLI] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.[HAMAP-Rule:MF_00163]
-
 
+
== Evolutionary Conservation ==
-
<!--
+
[[Image:Consurf_key_small.gif|200px|right]]
-
The line below this paragraph, {{ABSTRACT_PUBMED_15796505}}, adds the Publication Abstract to the page
+
Check<jmol>
-
(as it appears on PubMed at http://www.pubmed.gov), where 15796505 is the PubMed ID number.
+
<jmolCheckbox>
-
-->
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xe/1xen_consurf.spt"</scriptWhenChecked>
-
{{ABSTRACT_PUBMED_15796505}}
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
 
+
<text>to colour the structure by Evolutionary Conservation</text>
-
==About this Structure==
+
</jmolCheckbox>
-
1XEN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XEN OCA].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xen ConSurf].
-
 
+
<div style="clear:both"></div>
-
==Reference==
+
__TOC__
-
Structures of E. coli peptide deformylase bound to formate: insight into the preference for Fe2+ over Zn2+ as the active site metal., Jain R, Hao B, Liu RP, Chan MK, J Am Chem Soc. 2005 Apr 6;127(13):4558-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15796505 15796505]
+
</StructureSection>
-
[[Category: Escherichia coli]]
+
[[Category: Large Structures]]
-
[[Category: Peptide deformylase]]
+
[[Category: Chan MK]]
-
[[Category: Single protein]]
+
[[Category: Hao B]]
-
[[Category: Chan, M K.]]
+
[[Category: Jain R]]
-
[[Category: Hao, B.]]
+
[[Category: Liu R-P]]
-
[[Category: Jain, R.]]
+
-
[[Category: Liu, R P.]]
+
-
[[Category: Formate]]
+
-
[[Category: Iron deformylase]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 20:26:49 2008''
+

Current revision

High Resolution Crystal Structure of Escherichia coli Iron- Peptide Deformylase Bound To Formate

PDB ID 1xen

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1xen"
Personal tools