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1xpp

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[[Image:1xpp.jpg|left|200px]]
 
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{{Structure
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==Crystal Structure of TA1416,DNA-directed RNA polymerase subunit L, from Thermoplasma acidophilum==
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|PDB= 1xpp |SIZE=350|CAPTION= <scene name='initialview01'>1xpp</scene>, resolution 1.60&Aring;
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<StructureSection load='1xpp' size='340' side='right'caption='[[1xpp]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene>
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<table><tr><td colspan='2'>[[1xpp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermoplasma_acidophilum Thermoplasma acidophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XPP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XPP FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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|GENE= rpoL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2303 Thermoplasma acidophilum])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK01146 PRK01146]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xpp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xpp OCA], [https://pdbe.org/1xpp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xpp RCSB], [https://www.ebi.ac.uk/pdbsum/1xpp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xpp ProSAT], [https://www.topsan.org/Proteins/MCSG/1xpp TOPSAN]</span></td></tr>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xpp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xpp OCA], [http://www.ebi.ac.uk/pdbsum/1xpp PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=1xpp RCSB]</span>
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</table>
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}}
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== Function ==
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[https://www.uniprot.org/uniprot/RPO11_THEAC RPO11_THEAC] DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_00261]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xp/1xpp_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xpp ConSurf].
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<div style="clear:both"></div>
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'''Crystal Structure of TA1416,DNA-directed RNA polymerase subunit L, from Thermoplasma acidophilum'''
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==See Also==
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*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1XPP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermoplasma_acidophilum Thermoplasma acidophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XPP OCA].
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[[Category: Large Structures]]
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[[Category: DNA-directed RNA polymerase]]
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[[Category: Single protein]]
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[[Category: Thermoplasma acidophilum]]
[[Category: Thermoplasma acidophilum]]
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[[Category: Edwards, A.]]
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[[Category: Edwards A]]
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[[Category: Evdokimova, E.]]
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[[Category: Evdokimova E]]
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[[Category: Joachimiak, A.]]
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[[Category: Joachimiak A]]
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[[Category: Kim, Y.]]
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[[Category: Kim Y]]
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[[Category: Savchenko A]]
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[[Category: Savchenko, A.]]
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[[Category: dna-directed rna polymerase]]
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[[Category: mcsg]]
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[[Category: midwest center for structural genomic]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: structural genomic]]
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[[Category: thermoplasma acidophilum]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:12:24 2008''
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Current revision

Crystal Structure of TA1416,DNA-directed RNA polymerase subunit L, from Thermoplasma acidophilum

PDB ID 1xpp

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