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1ya9
From Proteopedia
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| - | [[Image:1ya9.png|left|200px]] | ||
| - | + | ==Crystal Structure of the 22kDa N-Terminal Fragment of Mouse Apolipoprotein E== | |
| - | + | <StructureSection load='1ya9' size='340' side='right'caption='[[1ya9]], [[Resolution|resolution]] 2.09Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1ya9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YA9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YA9 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.09Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ya9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ya9 OCA], [https://pdbe.org/1ya9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ya9 RCSB], [https://www.ebi.ac.uk/pdbsum/1ya9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ya9 ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[1ya9]] is a 1 chain structure with sequence from [ | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/APOE_MOUSE APOE_MOUSE] Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues. | |
| - | == | + | == Evolutionary Conservation == |
| - | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ya/1ya9_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ya9 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Hatters | + | [[Category: Hatters DM]] |
| - | [[Category: Newhouse | + | [[Category: Newhouse Y]] |
| - | [[Category: Peters-Libeu | + | [[Category: Peters-Libeu CA]] |
| - | [[Category: Rutenber | + | [[Category: Rutenber E]] |
| - | [[Category: Weisgraber | + | [[Category: Weisgraber KH]] |
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Current revision
Crystal Structure of the 22kDa N-Terminal Fragment of Mouse Apolipoprotein E
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