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1ya9

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{{Seed}}
 
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[[Image:1ya9.png|left|200px]]
 
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==Crystal Structure of the 22kDa N-Terminal Fragment of Mouse Apolipoprotein E==
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The line below this paragraph, containing "STRUCTURE_1ya9", creates the "Structure Box" on the page.
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<StructureSection load='1ya9' size='340' side='right'caption='[[1ya9]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1ya9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YA9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YA9 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.09&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ya9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ya9 OCA], [https://pdbe.org/1ya9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ya9 RCSB], [https://www.ebi.ac.uk/pdbsum/1ya9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ya9 ProSAT]</span></td></tr>
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{{STRUCTURE_1ya9| PDB=1ya9 | SCENE= }}
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</table>
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== Function ==
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===Crystal Structure of the 22kDa N-Terminal Fragment of Mouse Apolipoprotein E===
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[https://www.uniprot.org/uniprot/APOE_MOUSE APOE_MOUSE] Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_15890642}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 15890642 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ya/1ya9_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_15890642}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ya9 ConSurf].
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1YA9 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YA9 OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:15890642</ref><references group="xtra"/>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Hatters, D M.]]
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[[Category: Hatters DM]]
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[[Category: Newhouse, Y.]]
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[[Category: Newhouse Y]]
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[[Category: Peters-Libeu, C A.]]
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[[Category: Peters-Libeu CA]]
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[[Category: Rutenber, E.]]
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[[Category: Rutenber E]]
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[[Category: Weisgraber, K H.]]
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[[Category: Weisgraber KH]]
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[[Category: Apolipoprotein e]]
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[[Category: Ldl receptor binding]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 13:29:33 2009''
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Current revision

Crystal Structure of the 22kDa N-Terminal Fragment of Mouse Apolipoprotein E

PDB ID 1ya9

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