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1yhl

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[[Image:1yhl.png|left|200px]]
 
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==Structure of the complex of Trypanosoma cruzi farnesyl diphosphate synthase with risedronate, dmapp and mg+2==
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The line below this paragraph, containing "STRUCTURE_1yhl", creates the "Structure Box" on the page.
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<StructureSection load='1yhl' size='340' side='right'caption='[[1yhl]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1yhl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YHL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YHL FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMA:DIMETHYLALLYL+DIPHOSPHATE'>DMA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=RIS:1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE+BIS-PHOSPHONIC+ACID'>RIS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1yhl| PDB=1yhl | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yhl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yhl OCA], [https://pdbe.org/1yhl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yhl RCSB], [https://www.ebi.ac.uk/pdbsum/1yhl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yhl ProSAT]</span></td></tr>
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</table>
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===Structure of the complex of Trypanosoma cruzi farnesyl diphosphate synthase with risedronate, dmapp and mg+2===
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== Function ==
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[https://www.uniprot.org/uniprot/Q8WS26_TRYCR Q8WS26_TRYCR]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_16288456}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 16288456 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yh/1yhl_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_16288456}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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[[1yhl]] is a 1 chain structure of [[Farnesyl diphosphate synthase]] with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YHL OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yhl ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Farnesyl diphosphate synthase|Farnesyl diphosphate synthase]]
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*[[Farnesyl diphosphate synthase 3D structures|Farnesyl diphosphate synthase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:016288456</ref><ref group="xtra">PMID:019245203</ref><references group="xtra"/>
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[[Category: Large Structures]]
[[Category: Trypanosoma cruzi]]
[[Category: Trypanosoma cruzi]]
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[[Category: Amzel, L M.]]
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[[Category: Amzel LM]]
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[[Category: Docampo, R.]]
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[[Category: Docampo R]]
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[[Category: Gabelli, S B.]]
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[[Category: Gabelli SB]]
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[[Category: McLellan, J S.]]
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[[Category: McLellan JS]]
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[[Category: Montalvetti, A.]]
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[[Category: Montalvetti A]]
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[[Category: Oldfield, E.]]
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[[Category: Oldfield E]]
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[[Category: Bisphosphonate]]
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[[Category: Dimethyl allyl pyrophosphate sulfate]]
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[[Category: Farnesyl diphosphate synthase]]
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[[Category: Fpp]]
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[[Category: Transferase]]
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Current revision

Structure of the complex of Trypanosoma cruzi farnesyl diphosphate synthase with risedronate, dmapp and mg+2

PDB ID 1yhl

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