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1ymy

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[[Image:1ymy.gif|left|200px]]
 
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{{Structure
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==Crystal Structure of the N-Acetylglucosamine-6-phosphate deacetylase from Escherichia coli K12==
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|PDB= 1ymy |SIZE=350|CAPTION= <scene name='initialview01'>1ymy</scene>, resolution 2.6&Aring;
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<StructureSection load='1ymy' size='340' side='right'caption='[[1ymy]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[1ymy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YMY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YMY FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acetylglucosamine-6-phosphate_deacetylase N-acetylglucosamine-6-phosphate deacetylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.25 3.5.1.25] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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|GENE= nagA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ymy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ymy OCA], [https://pdbe.org/1ymy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ymy RCSB], [https://www.ebi.ac.uk/pdbsum/1ymy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ymy ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1ymy TOPSAN]</span></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1228 HutI], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00854 NagA]</span>
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ymy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ymy OCA], [http://www.ebi.ac.uk/pdbsum/1ymy PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=1ymy RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/NAGA_ECOLI NAGA_ECOLI] Catalyzes the deacetylation of N-acetyl-D-glucosamine-6-phosphate. In vitro, can also hydrolyze substrate analogs such as N-thioacetyl-D-glucosamine-6-phosphate, N-trifluoroacetyl-D-glucosamine-6-phosphate, N-acetyl-D-glucosamine-6-sulfate, N-acetyl-D-galactosamine-6-phosphate, and N-formyl-D-glucosamine-6-phosphate.<ref>PMID:17567047</ref>
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== Evolutionary Conservation ==
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'''Crystal Structure of the N-Acetylglucosamine-6-phosphate deacetylase from Escherichia coli K12'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ym/1ymy_consurf.spt"</scriptWhenChecked>
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1YMY is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YMY OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Escherichia coli]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: N-acetylglucosamine-6-phosphate deacetylase]]
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</jmolCheckbox>
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[[Category: Single protein]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ymy ConSurf].
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[[Category: Almo, S C.]]
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<div style="clear:both"></div>
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[[Category: Burley, S K.]]
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== References ==
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[[Category: Fedorov, A A.]]
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<references/>
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[[Category: Fedorov, E V.]]
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__TOC__
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[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
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</StructureSection>
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[[Category: Raushel, F M.]]
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[[Category: Escherichia coli K-12]]
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[[Category: Xiang, D F.]]
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[[Category: Large Structures]]
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[[Category: naga]]
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[[Category: Almo SC]]
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[[Category: new york structural genomix research consortium]]
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[[Category: Burley SK]]
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[[Category: nysgxrc target t2187]]
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[[Category: Fedorov AA]]
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[[Category: protein structure initiative]]
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[[Category: Fedorov EV]]
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[[Category: psi]]
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[[Category: Raushel FM]]
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[[Category: structural genomic]]
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[[Category: Xiang DF]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:15:31 2008''
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Current revision

Crystal Structure of the N-Acetylglucosamine-6-phosphate deacetylase from Escherichia coli K12

PDB ID 1ymy

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