1yu0

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{{Seed}}
 
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[[Image:1yu0.png|left|200px]]
 
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==Major Tropism Determinant P1 Variant==
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The line below this paragraph, containing "STRUCTURE_1yu0", creates the "Structure Box" on the page.
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<StructureSection load='1yu0' size='340' side='right'caption='[[1yu0]], [[Resolution|resolution]] 1.56&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1yu0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bordetella_virus_BPP1 Bordetella virus BPP1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YU0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YU0 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.56&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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{{STRUCTURE_1yu0| PDB=1yu0 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yu0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yu0 OCA], [https://pdbe.org/1yu0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yu0 RCSB], [https://www.ebi.ac.uk/pdbsum/1yu0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yu0 ProSAT]</span></td></tr>
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</table>
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===Major Tropism Determinant P1 Variant===
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== Function ==
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[https://www.uniprot.org/uniprot/FIBD_BPBPP FIBD_BPBPP] Tail fiber protein located at the distal ends of the fibers that binds to the adhesion receptors on the host surface, thereby determining the host range. The phage can alter its tropism by modifying this protein. Variants are expressed through a diversity-generating retroelement (DGR) that creates mutant copies of a template repeat and replaces the end of the tail fiber receptor-binding protein with these sequences, thus changing the host range. Milliards of variants of the fiber receptor-binding protein can be created with this system.<ref>PMID:15386016</ref>
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== References ==
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<references/>
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 16170324 is the PubMed ID number.
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</StructureSection>
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[[Category: Bordetella virus BPP1]]
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{{ABSTRACT_PUBMED_16170324}}
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[[Category: Large Structures]]
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[[Category: Ghosh P]]
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==About this Structure==
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[[Category: Lawton JA]]
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1YU0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YU0 OCA].
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[[Category: McMahon SA]]
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[[Category: Miller JL]]
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==Reference==
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The C-type lectin fold as an evolutionary solution for massive sequence variation., McMahon SA, Miller JL, Lawton JA, Kerkow DE, Hodes A, Marti-Renom MA, Doulatov S, Narayanan E, Sali A, Miller JF, Ghosh P, Nat Struct Mol Biol. 2005 Oct;12(10):886-92. Epub 2005 Sep 18. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16170324 16170324]
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[[Category: Single protein]]
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[[Category: Viruses]]
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[[Category: Ghosh, P.]]
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[[Category: Lawton, J A.]]
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[[Category: McMahon, S A.]]
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[[Category: Miller, J L.]]
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[[Category: Beta prism]]
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[[Category: Beta sandwich]]
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[[Category: C-type lectin]]
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[[Category: Diversity-generating retroelement]]
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[[Category: Variability]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 03:29:22 2008''
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Current revision

Major Tropism Determinant P1 Variant

PDB ID 1yu0

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