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1yvf

From Proteopedia

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[[Image:1yvf.png|left|200px]]
 
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{{STRUCTURE_1yvf| PDB=1yvf | SCENE= }}
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==Hepatitis C virus NS5B RNA-dependent RNA polymerase complex with inhibitor PHA-00729145==
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<StructureSection load='1yvf' size='340' side='right'caption='[[1yvf]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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===Hepatitis C virus NS5B RNA-dependent RNA polymerase complex with inhibitor PHA-00729145===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1yvf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepacivirus_C Hepacivirus C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YVF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YVF FirstGlance]. <br>
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{{ABSTRACT_PUBMED_15863301}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PH7:(2Z)-2-(BENZOYLAMINO)-3-[4-(2-BROMOPHENOXY)PHENYL]-2-PROPENOIC+ACID'>PH7</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yvf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yvf OCA], [https://pdbe.org/1yvf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yvf RCSB], [https://www.ebi.ac.uk/pdbsum/1yvf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yvf ProSAT]</span></td></tr>
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[[1yvf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YVF OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/O93077_9HEPC O93077_9HEPC]
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<ref group="xtra">PMID:015863301</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Category: Hepatitis c virus]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: RNA-directed RNA polymerase]]
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Check<jmol>
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[[Category: Anstadt, R A.]]
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<jmolCheckbox>
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[[Category: Finzel, B C.]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yv/1yvf_consurf.spt"</scriptWhenChecked>
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[[Category: Greene, M L.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Gross, R J.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Harris, M S.]]
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</jmolCheckbox>
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[[Category: Kilkuskie, R E.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yvf ConSurf].
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[[Category: Kopta, L A.]]
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<div style="clear:both"></div>
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[[Category: Mitchell, M A.]]
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__TOC__
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[[Category: Nugent, R A.]]
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</StructureSection>
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[[Category: Pfefferkorn, J A.]]
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[[Category: Hepacivirus C]]
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[[Category: Schwende, F J.]]
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[[Category: Large Structures]]
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[[Category: Shelly, J A.]]
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[[Category: Anstadt RA]]
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[[Category: Wells, P A.]]
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[[Category: Finzel BC]]
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[[Category: Finger]]
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[[Category: Greene ML]]
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[[Category: Hcv]]
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[[Category: Gross RJ]]
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[[Category: Ns5b]]
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[[Category: Harris MS]]
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[[Category: Palm]]
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[[Category: Kilkuskie RE]]
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[[Category: Polymerase]]
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[[Category: Kopta LA]]
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[[Category: Thumb]]
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[[Category: Mitchell MA]]
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[[Category: Transferase]]
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[[Category: Nugent RA]]
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[[Category: Pfefferkorn JA]]
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[[Category: Schwende FJ]]
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[[Category: Shelly JA]]
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[[Category: Wells PA]]

Current revision

Hepatitis C virus NS5B RNA-dependent RNA polymerase complex with inhibitor PHA-00729145

PDB ID 1yvf

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