This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1z3i

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:02, 14 February 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1z3i.png|left|200px]]
 
-
<!--
+
==Structure of the SWI2/SNF2 chromatin remodeling domain of eukaryotic Rad54==
-
The line below this paragraph, containing "STRUCTURE_1z3i", creates the "Structure Box" on the page.
+
<StructureSection load='1z3i' size='340' side='right'caption='[[1z3i]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1z3i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Danio_rerio Danio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z3I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z3I FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
{{STRUCTURE_1z3i| PDB=1z3i | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z3i OCA], [https://pdbe.org/1z3i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z3i RCSB], [https://www.ebi.ac.uk/pdbsum/1z3i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z3i ProSAT]</span></td></tr>
-
 
+
</table>
-
===Structure of the SWI2/SNF2 chromatin remodeling domain of eukaryotic Rad54===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/RAD54_DANRE RAD54_DANRE] Plays an essential role in homologous recombination (HR) which is a major pathway for repairing DNA double-strand breaks (DSBs), single-stranded DNA (ssDNA) gaps, and stalled or collapsed replication forks (PubMed:30961891). Acts as a molecular motor during the homology search and guides RAD51 ssDNA along a donor dsDNA thereby changing the homology search from the diffusion-based mechanism to a motor-guided mechanism. Also plays an essential role in RAD51-mediated synaptic complex formation which consists of three strands encased in a protein filament formed once homology is recognized. Once DNA strand exchange occured, dissociates RAD51 from nucleoprotein filaments formed on dsDNA (By similarity).[UniProtKB:P32863]<ref>PMID:30961891</ref>
-
 
+
== Evolutionary Conservation ==
-
<!--
+
[[Image:Consurf_key_small.gif|200px|right]]
-
The line below this paragraph, {{ABSTRACT_PUBMED_15806108}}, adds the Publication Abstract to the page
+
Check<jmol>
-
(as it appears on PubMed at http://www.pubmed.gov), where 15806108 is the PubMed ID number.
+
<jmolCheckbox>
-
-->
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z3/1z3i_consurf.spt"</scriptWhenChecked>
-
{{ABSTRACT_PUBMED_15806108}}
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
 
+
<text>to colour the structure by Evolutionary Conservation</text>
-
==About this Structure==
+
</jmolCheckbox>
-
1Z3I is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Danio_rerio Danio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z3I OCA].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1z3i ConSurf].
-
 
+
<div style="clear:both"></div>
-
==Reference==
+
== References ==
-
Structure of the SWI2/SNF2 chromatin-remodeling domain of eukaryotic Rad54., Thoma NH, Czyzewski BK, Alexeev AA, Mazin AV, Kowalczykowski SC, Pavletich NP, Nat Struct Mol Biol. 2005 Apr;12(4):350-6. Epub 2005 Apr 3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15806108 15806108]
+
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Danio rerio]]
[[Category: Danio rerio]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Alexeev, A A.]]
+
[[Category: Alexeev AA]]
-
[[Category: Czyzewski, B K.]]
+
[[Category: Czyzewski BK]]
-
[[Category: Kowalczykowski, S C.]]
+
[[Category: Kowalczykowski SC]]
-
[[Category: Mazin, A V.]]
+
[[Category: Mazin AV]]
-
[[Category: Pavletich, N P.]]
+
[[Category: Pavletich NP]]
-
[[Category: Thoma, N H.]]
+
[[Category: Thoma NH]]
-
[[Category: Recombination atpase helicase]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 08:25:14 2008''
+

Current revision

Structure of the SWI2/SNF2 chromatin remodeling domain of eukaryotic Rad54

PDB ID 1z3i

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1z3i"
Personal tools