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1z7m

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[[Image:1z7m.png|left|200px]]
 
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{{STRUCTURE_1z7m| PDB=1z7m | SCENE= }}
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==ATP Phosphoribosyl transferase (HisZG ATP-PRTase) from Lactococcus lactis==
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<StructureSection load='1z7m' size='340' side='right'caption='[[1z7m]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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===ATP Phosphoribosyl transferase (HisZG ATP-PRTase) from Lactococcus lactis===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1z7m]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Lactococcus_lactis Lactococcus lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z7M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z7M FirstGlance]. <br>
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{{ABSTRACT_PUBMED_16051603}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=WO4:TUNGSTATE(VI)ION'>WO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z7m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z7m OCA], [https://pdbe.org/1z7m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z7m RCSB], [https://www.ebi.ac.uk/pdbsum/1z7m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z7m ProSAT]</span></td></tr>
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[[1z7m]] is a 8 chain structure of [[ATP Phosphoribosyl Transferase]] with sequence from [http://en.wikipedia.org/wiki/Lactococcus_lactis Lactococcus lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z7M OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HISZ_LACLA HISZ_LACLA] Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.[HAMAP-Rule:MF_00125]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z7/1z7m_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1z7m ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[ATP Phosphoribosyl Transferase|ATP Phosphoribosyl Transferase]]
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*[[ATP phosphoribosyl transferase 3D structures|ATP phosphoribosyl transferase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:016051603</ref><references group="xtra"/>
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[[Category: ATP phosphoribosyltransferase]]
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[[Category: Lactococcus lactis]]
[[Category: Lactococcus lactis]]
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[[Category: Champagne, K S.]]
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[[Category: Large Structures]]
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[[Category: Doublie, S.]]
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[[Category: Champagne KS]]
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[[Category: Francklyn, C S.]]
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[[Category: Doublie S]]
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[[Category: Larrabee, Y.]]
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[[Category: Francklyn CS]]
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[[Category: Sissler, M.]]
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[[Category: Larrabee Y]]
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[[Category: Allosteric]]
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[[Category: Sissler M]]
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[[Category: Atp-prt]]
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[[Category: Evolution]]
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[[Category: Histidine biosynthesis]]
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[[Category: Hiszg]]
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[[Category: Transferase]]
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Current revision

ATP Phosphoribosyl transferase (HisZG ATP-PRTase) from Lactococcus lactis

PDB ID 1z7m

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