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1zd1
From Proteopedia
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| - | [[Image:1zd1.gif|left|200px]]<br /><applet load="1zd1" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1zd1, resolution 2.24Å" /> | ||
| - | '''Human Sulfortransferase SULT4A1'''<br /> | ||
| - | == | + | ==Human Sulfortransferase SULT4A1== |
| - | + | <StructureSection load='1zd1' size='340' side='right'caption='[[1zd1]], [[Resolution|resolution]] 2.24Å' scene=''> | |
| - | [ | + | == Structural highlights == |
| - | [[ | + | <table><tr><td colspan='2'>[[1zd1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZD1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZD1 FirstGlance]. <br> |
| - | [[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.24Å</td></tr> |
| - | [[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> |
| - | [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zd1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zd1 OCA], [https://pdbe.org/1zd1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zd1 RCSB], [https://www.ebi.ac.uk/pdbsum/1zd1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zd1 ProSAT]</span></td></tr> |
| - | + | </table> | |
| - | [ | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/ST4A1_HUMAN ST4A1_HUMAN] Atypical sulfotransferase family member with very low affinity for 3'-phospho-5'-adenylyl sulfate (PAPS) and very low catalytic activity towards L-triiodothyronine, thyroxine, estrone, p-nitrophenol, 2-naphthylamine, and 2-beta-naphthol. May have a role in the metabolism of drugs and neurotransmitters in the CNS.<ref>PMID:17425406</ref> | |
| - | + | == Evolutionary Conservation == | |
| - | [ | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [ | + | Check<jmol> |
| - | [[ | + | <jmolCheckbox> |
| - | [ | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zd/1zd1_consurf.spt"</scriptWhenChecked> |
| - | [[ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | [ | + | <text>to colour the structure by Evolutionary Conservation</text> |
| - | + | </jmolCheckbox> | |
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zd1 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| + | *[[Sulfotransferase 3D structures|Sulfotransferase 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Arrowsmith CH]] | ||
| + | [[Category: Bochkarev A]] | ||
| + | [[Category: Dombrovski L]] | ||
| + | [[Category: Dong A]] | ||
| + | [[Category: Edwards AM]] | ||
| + | [[Category: Loppnau P]] | ||
| + | [[Category: Plotnikov AN]] | ||
| + | [[Category: Sundstrom M]] | ||
Current revision
Human Sulfortransferase SULT4A1
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