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1zog

From Proteopedia

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{{Seed}}
 
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[[Image:1zog.png|left|200px]]
 
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==Crystal structure of protein kinase CK2 in complex with TBB-derivatives==
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The line below this paragraph, containing "STRUCTURE_1zog", creates the "Structure Box" on the page.
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<StructureSection load='1zog' size='340' side='right'caption='[[1zog]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1zog]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZOG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZOG FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K37:4,5,6,7-TETRABROMO-2-(METHYLSULFANYL)-1H-BENZIMIDAZOLE'>K37</scene></td></tr>
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{{STRUCTURE_1zog| PDB=1zog | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zog FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zog OCA], [https://pdbe.org/1zog PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zog RCSB], [https://www.ebi.ac.uk/pdbsum/1zog PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zog ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CSK2A_MAIZE CSK2A_MAIZE] Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha chain contains the catalytic site.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zo/1zog_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zog ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of protein kinase CK2 in complex with TBB-derivatives===
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==See Also==
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*[[Casein kinase 3D structures|Casein kinase 3D structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_16298300}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 16298300 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16298300}}
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==About this Structure==
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1ZOG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZOG OCA].
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==Reference==
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Inspecting the structure-activity relationship of protein kinase CK2 inhibitors derived from tetrabromo-benzimidazole., Battistutta R, Mazzorana M, Sarno S, Kazimierczuk Z, Zanotti G, Pinna LA, Chem Biol. 2005 Nov;12(11):1211-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16298300 16298300]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Single protein]]
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[[Category: Zea mays]]
[[Category: Zea mays]]
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[[Category: Battistutta, R.]]
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[[Category: Battistutta R]]
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[[Category: Kazimierczuk, Z.]]
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[[Category: Kazimierczuk Z]]
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[[Category: Mazzorana, M.]]
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[[Category: Mazzorana M]]
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[[Category: Pinna, L A.]]
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[[Category: Pinna LA]]
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[[Category: Sarno, S.]]
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[[Category: Sarno S]]
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[[Category: Zanotti, G.]]
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[[Category: Zanotti G]]
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[[Category: Inhibitor]]
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[[Category: Pharmacophore]]
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[[Category: Protein kinase ck2]]
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[[Category: Tbb]]
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[[Category: Tetrabromo-benzimidazole]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 04:50:51 2008''
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Current revision

Crystal structure of protein kinase CK2 in complex with TBB-derivatives

PDB ID 1zog

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