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2btv

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[[Image:2btv.gif|left|200px]]<br /><applet load="2btv" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2btv, resolution 3.5&Aring;" />
 
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'''ATOMIC MODEL FOR BLUETONGUE VIRUS (BTV) CORE'''<br />
 
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==Overview==
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==ATOMIC MODEL FOR BLUETONGUE VIRUS (BTV) CORE==
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The structure of the core particle of bluetongue virus has been determined by X-ray crystallography at a resolution approaching 3.5 A. This transcriptionally active compartment, 700 A in diameter, represents the largest molecular structure determined in such detail. The atomic structure indicates how approximately 1,000 protein components self-assemble, using both the classical mechanism of quasi-equivalent contacts, which are achieved through triangulation, and a different method, which we term geometrical quasi-equivalence.
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<SX load='2btv' size='340' side='right' viewer='molstar' caption='[[2btv]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2btv]] is a 15 chain structure with sequence from [https://en.wikipedia.org/wiki/Bluetongue_virus_(serotype_1_/_isolate_South_Africa) Bluetongue virus (serotype 1 / isolate South Africa)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BTV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BTV FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2btv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2btv OCA], [https://pdbe.org/2btv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2btv RCSB], [https://www.ebi.ac.uk/pdbsum/2btv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2btv ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/VP3_BTV1S VP3_BTV1S] The VP3 protein is one of the five proteins (with VP1, VP4, VP6 and VP7) which form the inner capsid of the virus.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bt/2btv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2btv ConSurf].
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<div style="clear:both"></div>
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==About this Structure==
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==See Also==
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2BTV is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Bluetongue_virus Bluetongue virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BTV OCA].
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*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
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__TOC__
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==Reference==
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</SX>
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The atomic structure of the bluetongue virus core., Grimes JM, Burroughs JN, Gouet P, Diprose JM, Malby R, Zientara S, Mertens PP, Stuart DI, Nature. 1998 Oct 1;395(6701):470-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9774103 9774103]
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[[Category: Large Structures]]
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[[Category: Bluetongue virus]]
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[[Category: Burroughs JN]]
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[[Category: Protein complex]]
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[[Category: Diprose JM]]
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[[Category: Burroughs, J N.]]
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[[Category: Gouet P]]
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[[Category: Diprose, J M.]]
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[[Category: Grimes JM]]
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[[Category: Gouet, P.]]
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[[Category: Malby R]]
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[[Category: Grimes, J M.]]
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[[Category: Mertens PPC]]
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[[Category: Malby, R.]]
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[[Category: Stuart DI]]
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[[Category: Mertens, P P.C.]]
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[[Category: Zientras S]]
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[[Category: Stuart, D I.]]
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[[Category: Zientras, S.]]
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[[Category: icosahedral virus]]
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[[Category: virus/viral protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:41:35 2008''
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Current revision

ATOMIC MODEL FOR BLUETONGUE VIRUS (BTV) CORE

2btv, resolution 3.50Å

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OCA

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