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2c0w

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[[Image:2c0w.gif|left|200px]]<br /><applet load="2c0w" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2c0w, resolution 3.2&Aring;" />
 
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'''MOLECULAR STRUCTURE OF FD FILAMENTOUS BACTERIOPHAGE REFINED WITH RESPECT TO X-RAY FIBRE DIFFRACTION'''<br />
 
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==Overview==
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==Molecular Structure of fd Filamentous Bacteriophage Refined with Respect to X-ray Fibre Diffraction==
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Filamentous bacteriophage (Inovirus) is a simple and well-characterized model system. The phage particle, or virion, is about 60 angstroms in diameter and several thousand angstrom units long. The virions are assembled at the bacterial membrane as they extrude out of the host without killing it, an example of specific transport of nucleoprotein assemblages across membranes. The Ff group (fd, f1 and M13) has been especially widely studied. Models of virion assembly have been proposed based on a molecular model of the fd virion derived by X-ray fibre diffraction. A somewhat different model of the fd virion using solid-state NMR data has been proposed, not consistent with these models of assembly nor with the X-ray diffraction data. Here we show that reinterpreted NMR data are also consistent with the model derived from X-ray fibre diffraction studies, and discuss models of virion assembly.
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<StructureSection load='2c0w' size='340' side='right'caption='[[2c0w]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[2c0w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterobacteria_phage_fd Enterobacteria phage fd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C0W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C0W FirstGlance]. <br>
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2C0W is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Phage_phi3t Phage phi3t]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C0W OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Fiber diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c0w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c0w OCA], [https://pdbe.org/2c0w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c0w RCSB], [https://www.ebi.ac.uk/pdbsum/2c0w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c0w ProSAT]</span></td></tr>
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==Reference==
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</table>
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Molecular structure of fd (f1, M13) filamentous bacteriophage refined with respect to X-ray fibre diffraction and solid-state NMR data supports specific models of phage assembly at the bacterial membrane., Marvin DA, Welsh LC, Symmons MF, Scott WR, Straus SK, J Mol Biol. 2006 Jan 13;355(2):294-309. Epub 2005 Nov 8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16300790 16300790]
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== Function ==
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[[Category: Phage phi3t]]
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[https://www.uniprot.org/uniprot/CAPSD_BPFD CAPSD_BPFD] Self assembles to form a helical capsid wrapping up the viral genomic DNA. The capsid displays a filamentous structure with a length of 760-1950 nm and a width of 6-8 nm. The virion assembly and budding take place at the host inner membrane (By similarity).
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[[Category: Single protein]]
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__TOC__
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[[Category: Marvin, D A.]]
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</StructureSection>
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[[Category: Scott, W R.P.]]
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[[Category: Enterobacteria phage fd]]
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[[Category: Straus, S K.]]
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[[Category: Large Structures]]
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[[Category: Symmons, M F.]]
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[[Category: Marvin DA]]
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[[Category: Welsh, L C.]]
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[[Category: Scott WRP]]
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[[Category: alpha-helix]]
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[[Category: Straus SK]]
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[[Category: capsid protein]]
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[[Category: Symmons MF]]
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[[Category: filamentous bacteriophage]]
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[[Category: Welsh LC]]
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[[Category: helical virus]]
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[[Category: membrane proteins]]
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[[Category: structural protein]]
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[[Category: transmembrane]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:43:53 2008''
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Current revision

Molecular Structure of fd Filamentous Bacteriophage Refined with Respect to X-ray Fibre Diffraction

PDB ID 2c0w

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